Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9421996 | 0.72 | — | — | |
| SCHEMBL25953602 | 0.70 | GAA (0.33) | GAA | |
| SCHEMBL4530241 | 0.70 | GAA (0.30) | GAA | |
| SCHEMBL19370233 | 0.65 | GAA (0.33) | GAA | |
| SCHEMBL26005630 | 0.65 | NOS3 (0.35) | NOS3NOS2 | |
| SCHEMBL11580484 | 0.65 | NOS3 (0.38) | NOS3NOS2KDM4EPOLB | |
| SCHEMBL12797847 | 0.65 | NOS3 (0.35) | NOS3NOS2 | |
| SCHEMBL12484463 | 0.63 | HEXA (0.48) | — | |
| SCHEMBL12705668 | 0.63 | HEXA (0.44) | — | |
| SCHEMBL395140 | 0.62 | NOS3 (0.33) | NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2944637-B1 | NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF | FUJIFILM CORP (JP) | 2020-02-19 | — | — | EP | disclosed |
| EP-2944637-A1 | NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF | FUJIFILM Corporation (JP) | 2015-11-18 | — | — | EP | disclosed |