Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17255366 | 0.84 | CA2 (0.40) | CA12CA1CA2CA9CA14 | |
| SCHEMBL21962575 | 0.83 | GPR119 (0.50) | GPR119NR1H2NR1H3CA12CA1 | |
| SCHEMBL21962692 | 0.77 | GPR119 (0.49) | GPR119NR1H2NR1H3CA12CA1 | |
| SCHEMBL16409297 | 0.76 | CA2 (0.51) | GPR119NR1H2NR1H3CA12CA1 | |
| SCHEMBL17782219 | 0.75 | NR1H2 (0.51) | GPR119NR1H2NR1H3CA12CA1 | |
| SCHEMBL21319501 | 0.75 | NPSR1 (0.52) | LMNANPSR1 | |
| SCHEMBL13740405 | 0.75 | NPSR1 (0.52) | LMNANPSR1MEN1KMT2A | |
| SCHEMBL13740760 | 0.72 | HSP90AA1 (0.62) | LMNANPSR1MEN1KMT2AHSD11B1 | |
| SCHEMBL25594973 | 0.71 | LMNA (0.48) | NR1H2LMNANPSR1 | |
| SCHEMBL20170496 | 0.71 | HSP90AA1 (0.56) | LMNANPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2944637-B1 | NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF | FUJIFILM CORP (JP) | 2020-02-19 | — | — | EP | disclosed |
| EP-2944637-A1 | NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF | FUJIFILM Corporation (JP) | 2015-11-18 | — | — | EP | disclosed |