Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HEXA | P06865 | 1/20 | 0.32 |
| ▸ | HEXB | P07686 | 1/20 | 0.32 |
| ▸ | USP7 | Q93009 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6162685 | 0.75 | KDM4E (0.34) | MAPK1RECQLNOS2KDM4EALDH1A1 | |
| SCHEMBL17255291 | 0.71 | NOS3 (0.34) | NOS2KDM4EPOLB | |
| SCHEMBL5187789 | 0.68 | NOS2 (0.39) | MAPK1RECQLNOS2KDM4EPOLB | |
| SCHEMBL27544017 | 0.67 | HEXA (0.49) | MAPK1RECQLNOS2KDM4EPOLB | |
| SCHEMBL27902447 | 0.65 | KDM4E (0.32) | NOS2KDM4EALDH1A1 | |
| SCHEMBL28257259 | 0.65 | NOS2 (0.40) | NOS2KDM4EALDH1A1USP7 | |
| SCHEMBL6024863 | 0.64 | NOS2 (0.39) | MAPK1RECQLNOS2KDM4EPOLB | |
| SCHEMBL3285596 | 0.64 | NOS2 (0.47) | NOS2KDM4EUSP7 | |
| SCHEMBL841074 | 0.64 | NOS2 (0.37) | MAPK1RECQLNOS2KDM4EALDH1A1 | |
| SCHEMBL12668092 | 0.64 | KDM4E (0.32) | NOS2KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2944637-B1 | NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF | FUJIFILM CORP (JP) | 2020-02-19 | — | — | EP | disclosed |
| EP-2944637-A1 | NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF | FUJIFILM Corporation (JP) | 2015-11-18 | — | — | EP | disclosed |
| CN-104903320-A | Nitrogen-containing heterocylic compound or salt thereof | FUJIFILM CORP | 2015-09-09 | — | — | CN | disclosed |