SCHEMBL172555

SCHEMBL172555

C=CC(=C)OCc1ccc(N(c2ccc(OC(=O)C(=C)C)cc2)c2ccc(Oc3ccccc3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.43
NR3C1 P04150 1/20 0.37
MMP2 P08253 1/20 0.37
PPARG P37231 1/20 0.37
THRB P10828 2/20 0.36
FFAR1 O14842 3/20 0.36
FFAR4 Q5NUL3 1/20 0.36
TGM2 P21980 2/20 0.36
F13A1 P00488 1/20 0.36
TGM1 P22735 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
ALDH1A1 P00352 2/20 0.35
HPGD P15428 2/20 0.34
SRD5A2 P31213 1/20 0.34
NPC1 O15118 1/20 0.34
CRHBP P24387 1/20 0.34
RAB9A P51151 1/20 0.34
CRHR2 Q13324 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11987088 0.92 ELANE (0.43) ELANENR3C1MMP2PPARGTHRB
SCHEMBL170754 0.90 ELANE (0.48) ELANENR3C1MMP2PPARGFFAR1
SCHEMBL12934690 0.89 ALDH1A1 (0.48) ELANENR3C1MMP2PPARGFFAR1
SCHEMBL11987094 0.88 THRB (0.45) ELANENR3C1MMP2PPARGTHRB
SCHEMBL11987078 0.86 ELANE (0.46) ELANETHRBSMN1; SMN2ALDH1A1HPGD
SCHEMBL11987103 0.85 NR3C1 (0.44) NR3C1MMP2PPARGFFAR1FFAR4
SCHEMBL11987104 0.85 THRB (0.40) NR3C1MMP2PPARGTHRBFFAR1
SCHEMBL12234097 0.84 ELANE (0.51) ELANEMMP2THRBTGM2SMN1; SMN2
SCHEMBL172208 0.84 ELANE (0.51) ELANESMN1; SMN2ALDH1A1HPGDNPC1
SCHEMBL12234116 0.84 ELANE (0.59) ELANENR3C1MMP2FFAR1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1847881-B1 Image forming apparatus, image forming method, and process cartridge RICOH CO LTD (JP) 2012-03-07 EP disclosed