SCHEMBL172562

SCHEMBL172562

C=CC(=O)Oc1ccc(-c2ccc(N(c3ccc(OC(=O)C=C)cc3)c3ccc(C)c(CCCC)c3)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ THRB P10828 4/20 0.50
▸ THRA P10827 2/20 0.44
▸ TSHR P16473 2/20 0.35
▸ HPGD P15428 1/20 0.35
▸ PDE6D O43924 1/20 0.33
▸ RARB P10826 7/20 0.33
▸ CNR1 P21554 2/20 0.32
▸ CNR2 P34972 2/20 0.32
▸ RARA P10276 1/20 0.32
▸ PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13968315 1.00 THRB (0.50) THRBTHRATSHRHPGDPDE6D
SCHEMBL14402819 0.93 THRB (0.44) THRBTHRATSHRHPGDPDE6D
SCHEMBL14402957 0.93 THRB (0.44) THRBTHRATSHRHPGDPDE6D
SCHEMBL14402956 0.93 THRB (0.44) THRBTHRATSHRHPGDPDE6D
SCHEMBL170675 0.88 THRB (0.51) THRBTHRATSHRHPGD
SCHEMBL13778859 0.86 THRB (0.43) THRBTHRATSHRPDE6D
SCHEMBL14402755 0.85 ELANE (0.37) THRBRARBCNR1CNR2RARA
SCHEMBL14402958 0.85 ELANE (0.37) THRBRARBCNR1CNR2RARA
SCHEMBL172441 0.84 THRB (0.47) THRBTHRATSHRHPGD
SCHEMBL27715804 0.84 THRB (0.57) THRBTHRATSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1847881-B1 Image forming apparatus, image forming method, and process cartridge RICOH CO LTD (JP) 2012-03-07 — — EP disclosed
EP-1847881-A2 Image forming apparatus, image forming method, and process cartridge Ricoh Company, Ltd. (JP) 2007-10-24 — — EP disclosed
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