SCHEMBL172441

SCHEMBL172441

C=CC(=O)Oc1ccc(N(c2ccc(COC(=O)C(=C)C)cc2)c2ccc(C)c(CCCC)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ THRB P10828 4/20 0.47
▸ THRA P10827 2/20 0.37
▸ TGM2 P21980 1/20 0.32
▸ TSHR P16473 3/20 0.31
▸ HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL172503 0.94 THRB (0.43) THRBTHRATGM2TSHRHPGD
SCHEMBL14402565 0.93 THRB (0.37) THRBTHRATGM2TSHRHPGD
SCHEMBL14402960 0.92 THRB (0.35) THRBTHRATSHR
SCHEMBL170675 0.91 THRB (0.51) THRBTHRATGM2TSHRHPGD
SCHEMBL14402961 0.90 TSHR (0.36) THRBTHRATGM2TSHRHPGD
SCHEMBL14402957 0.88 THRB (0.44) THRBTHRATSHRHPGD
SCHEMBL14402819 0.88 THRB (0.44) THRBTHRATSHRHPGD
SCHEMBL14402956 0.88 THRB (0.44) THRBTHRATSHRHPGD
SCHEMBL14402810 0.86 THRB (0.41) THRBTHRATGM2TSHRHPGD
SCHEMBL172562 0.84 THRB (0.50) THRBTHRATSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1847881-B1 Image forming apparatus, image forming method, and process cartridge RICOH CO LTD (JP) 2012-03-07 — — EP disclosed
EP-1847881-A2 Image forming apparatus, image forming method, and process cartridge Ricoh Company, Ltd. (JP) 2007-10-24 — — EP disclosed
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