SCHEMBL170675

SCHEMBL170675

C=CC(=O)OCc1ccc(N(c2ccc(OC(=O)C=C)cc2)c2ccc(C)c(CCCC)c2)cc1

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ THRB P10828 10/20 0.51
▸ THRA P10827 7/20 0.40
▸ TSHR P16473 2/20 0.36
▸ HPGD P15428 1/20 0.36
▸ TGM2 P21980 1/20 0.34
▸ CYP3A4 P08684 2/20 0.32
▸ CYP2D6 P10635 1/20 0.32
▸ CYP2C9 P11712 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.31
▸ MAPK1 P28482 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ NAAA Q02083 1/20 0.30
▸ ASAH1 Q13510 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14402810 0.95 THRB (0.41) THRBTHRATSHRHPGDTGM2
SCHEMBL172503 0.93 THRB (0.43) THRBTHRATSHRHPGDTGM2
SCHEMBL172441 0.91 THRB (0.47) THRBTHRATSHRHPGDTGM2
SCHEMBL13968315 0.88 THRB (0.50) THRBTHRATSHRHPGD
SCHEMBL172562 0.88 THRB (0.50) THRBTHRATSHRHPGD
SCHEMBL14402565 0.88 THRB (0.37) THRBTHRATSHRHPGDTGM2
SCHEMBL14402960 0.83 THRB (0.35) THRBTHRATSHRCYP3A4KMT2A
SCHEMBL2602538 0.82 THRB (0.56) THRBTHRATSHRHPGDCYP3A4
SCHEMBL14402819 0.82 THRB (0.44) THRBTHRATSHRHPGDKMT2A
SCHEMBL14402957 0.82 THRB (0.44) THRBTHRATSHRHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1847881-B1 Image forming apparatus, image forming method, and process cartridge RICOH CO LTD (JP) 2012-03-07 — — EP disclosed
EP-1847881-A2 Image forming apparatus, image forming method, and process cartridge Ricoh Company, Ltd. (JP) 2007-10-24 — — EP disclosed
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