Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL7455556 | 0.96 | LMNA (0.75) | LMNAALDH1A1TSHRTHRBTDP1 | |
| Glycerin SCHEMBL29231 | 0.96 | — | — | |
| Glycerin SCHEMBL2553942 | 0.96 | LMNA (0.75) | LMNAALDH1A1TSHRTHRBTDP1 | |
| Glycerin SCHEMBL5249319 | 0.96 | LMNA (0.75) | LMNAALDH1A1TSHRTHRBTDP1 | |
| Glycerin SCHEMBL8773344 | 0.96 | LMNA (0.75) | LMNAALDH1A1TSHRTHRBTDP1 | |
| Glycerin SCHEMBL23630291 | 0.92 | LMNA (0.69) | LMNAALDH1A1TSHRTHRBTDP1 | |
| Glycerin SCHEMBL8003351 | 0.92 | LMNA (0.69) | LMNAALDH1A1TSHRTHRBTDP1 | |
| Glycerin SCHEMBL1793735 | 0.92 | LMNA (0.69) | LMNAALDH1A1TSHRTHRBTDP1 | |
| Glycerin SCHEMBL27606425 | 0.92 | LMNA (0.69) | LMNAALDH1A1TSHRTHRBTDP1 | |
| Glycerin SCHEMBL28212896 | 0.92 | LMNA (0.82) | LMNAALDH1A1TSHRTHRBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10071952-B2 | Alpha/alpha-prime-alkoxylated glycerol linear carbonic esters | CHRYSO (FR) | 2018-09-11 | — | — | US | disclosed |
| US-20180179143-A1 | Alpha/alpha-prime-alkoxylated glycerol linear carbonic esters | STARCIN HOLDING FRANCE (FR) | 2018-06-28 | — | — | US | disclosed |
| US-9950988-B2 | Method for the synthesis of alpha/alpha-prime-alcoxylated glycerol linear carbonic esters | CHRYSO (FR) | 2018-04-24 | — | — | US | disclosed |
| US-20150329468-A1 | Method for the synthesis of alpha/alpha-prime-alcoxylated glycerol linear carbonic esters | STARCIN HOLDING FRANCE (FR) | 2015-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180179143-A1 | Alpha/alpha-prime-alkoxylated glycerol linear carbonic esters | EBP, P4HA1, GK | LMNA 785/4885ALDH1A1 512/4885TSHR 4197/4885 |
| US-20150329468-A1 | Method for the synthesis of alpha/alpha-prime-alcoxylated glycerol linear carbonic esters | POLL, GK, GLA | LMNA 778/4885ALDH1A1 748/4885TSHR 4758/4885 |
| US-10071952-B2 | Alpha/alpha-prime-alkoxylated glycerol linear carbonic esters | EBP, P4HA1, GK | LMNA 785/4885ALDH1A1 512/4885TSHR 4197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.