Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.75 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL5249319 | 1.00 | LMNA (0.75) | LMNAALDH1A1TSHRTHRBTDP1 | |
| Glycerin SCHEMBL2553942 | 1.00 | LMNA (0.75) | LMNAALDH1A1TSHRTHRBTDP1 | |
| Glycerin SCHEMBL29231 | 1.00 | — | — | |
| Glycerin SCHEMBL7455556 | 1.00 | LMNA (0.75) | LMNAALDH1A1TSHRTHRBTDP1 | |
| Glycerin SCHEMBL23630291 | 0.96 | LMNA (0.69) | LMNAALDH1A1TSHRTHRBTDP1 | |
| Glycerin SCHEMBL8003351 | 0.96 | LMNA (0.69) | LMNAALDH1A1TSHRTHRBTDP1 | |
| Glycerin SCHEMBL17256232 | 0.96 | LMNA (0.69) | LMNAALDH1A1TSHRTHRBTDP1 | |
| Glycerin SCHEMBL1793735 | 0.96 | LMNA (0.69) | LMNAALDH1A1TSHRTHRBTDP1 | |
| Glycerin SCHEMBL27606425 | 0.96 | LMNA (0.69) | LMNAALDH1A1TSHRTHRBTDP1 | |
| Glycerin SCHEMBL28552146 | 0.93 | LMNA (0.64) | LMNAALDH1A1TSHRTHRBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112203511-B | Macrocyclic tetrapyrrole compounds, compositions and methods for increasing abiotic stress resistance of plants | 桑科能源股份有限公司 | 2023-06-02 | — | — | CN | disclosed |
| WO-2021026947-A1 | COMBUSTIBLE ICE FAST SUPERCOOLING NANO LIQUEFACTION AGENT AND METHOD FOR MINING COMBUSTIBLE ICE | 成都能生材科技开发有限责任公司 | 2021-02-18 | — | — | WO | disclosed |
| EP-0316571-B2 | Process for preparation of porous shaped articles | TEIJIN LTD (JP) | 1997-11-05 | — | — | EP | disclosed |
| US-5198475-A | Rigid polyurethane foams and composites | MITSUI TOATSU CHEMICALS, INC. (JP) | 1993-03-30 | — | — | US | disclosed |
| US-4913864-A | MIXING, KNEADING, EXTRUSION MIXTURE OF POLYMER POWDER AND LIQUID | TEIJIN LIMITED (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0316571-A2 | Process for preparation of porous shaped articles | TEIJIN LIMITED (JP) | 1989-05-24 | — | — | EP | disclosed |