SCHEMBL1725673

SCHEMBL1725673

Nc1cc(Cl)c([N+](=O)[O-])cc1Cl

nearest known ligand 0.69

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.69
CYP3A4 P08684 2/20 0.69
GAA P10253 1/20 0.52
MAPT P10636 5/20 0.50
TDP1 Q9NUW8 4/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
TSHR P16473 2/20 0.50
MAPK1 P28482 1/20 0.50
PDE7A Q13946 2/20 0.47
LMNA P02545 1/20 0.47
VCAM1 P19320 2/20 0.47
POLB P06746 1/20 0.45
ALOX15 P16050 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7688649 0.91 ALDH1A1 (0.63) ALDH1A1CYP3A4GAAMAPTTDP1
SCHEMBL29596496 0.89 ALDH1A1 (0.71) ALDH1A1CYP3A4MAPTTDP1MEN1
SCHEMBL1192850 0.89 ALDH1A1 (0.71) ALDH1A1CYP3A4MAPTTDP1MEN1
SCHEMBL838256 0.89 ALDH1A1 (0.71) ALDH1A1CYP3A4MAPTTDP1MEN1
SCHEMBL11516256 0.88 ALDH1A1 (0.56) ALDH1A1CYP3A4GAAMAPTTDP1
SCHEMBL4090172 0.87 ALDH1A1 (0.58) ALDH1A1CYP3A4GAAMAPTTDP1
SCHEMBL8406658 0.87 MAPT (0.57) ALDH1A1CYP3A4GAAMAPTTDP1
SCHEMBL30606309 0.87 ALDH1A1 (0.58) ALDH1A1CYP3A4GAAMAPTTDP1
SCHEMBL11548194 0.87 ALDH1A1 (0.63) ALDH1A1CYP3A4MAPTTDP1MEN1
SCHEMBL9180125 0.86 TSHR (0.62) ALDH1A1CYP3A4TDP1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105836743-B A kind of preparation facilities of graphene powder and preparation method thereof 烟台市烯能新材料股份有限公司 2018-01-30 CN claimed
CN-105836743-A Preparation device and preparation method of graphene powder 烟台市烯能新材料股份有限公司 2016-08-10 CN claimed
EP-2084232-B1 DISPERSE AZO DYESTUFFS DYSTAR COLOURS DISTRIB GMBH (DE) 2012-08-15 EP claimed
US-7871446-B2 Disperse azo dyestuffs DyStar Colours Deutschland KG (DE) 2011-01-18 US claimed
US-20100009081-A1 3-{[4-(2-Chloro-4-nitrophenylazo)-phenyl]-ethyl-amino}-2-methyl-propionic acid vinyl ester; ink jet printing; dyeing and printing of synthetic textile material and fiber blends; dyeings on polyester with improved washfastness properties obtained if dyestuffs contain a vinyl ester group in coupling DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND (DE) 2010-01-14 US claimed
EP-2084232-A1 DISPERSE AZO DYESTUFFS DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2009-08-05 EP claimed
WO-2008055846-A1 DISPERSE AZO DYESTUFFS DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) 2008-05-15 WO claimed
EP-0416118-B1 PRODUCTION OF p-PHENYLENEDIAMINES NIPPON KAYAKU KK (JP) 1993-12-29 EP claimed
US-5041672-A Process for preparing p-phenylenediamines NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1991-08-20 US claimed
EP-0416118-A1 PRODUCTION OF p-PHENYLENEDIAMINES NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1991-03-13 EP claimed
US-4151203-A Process for the preparation of p-nitroaniline compounds by the alkaline hydrolysis of mixed anilides EASTMAN KODAK COMPANY (US) 1979-04-24 US claimed
WO-2025063626-A1 INFRARED-TRANSMISSIVE PHOTOSENSITIVE RESIN COMPOSITION, INFRARED-TRANSMISSIVE PIXEL, COLOR FILTER ARRAY, IMAGE SENSOR, AND LIDAR SENSOR 동우 화인켐 주식회사 2025-03-27 WO disclosed
WO-2025063731-A1 COLORED PHOTOSENSITIVE RESIN COMPOSITION, AND COLOR FILTER AND IMAGE DISPLAY DEVICE MANUFACTURED USING SAME 동우 화인켐 주식회사 2025-03-27 WO disclosed
CN-119264697-A Azo dye, colored curable resin composition, color filter, display device, solid-state imaging element, and method for producing azo dye 住友化学株式会社 2025-01-07 CN disclosed
CN-117430554-A Coloring composition and compound 住友化学株式会社 2024-01-23 CN disclosed
US-3978038-A POLYAMIDES, POLYESTERS, POLYURETHANES CIBA-GEIGY CORPORATION (US) 1976-08-31 US disclosed
US-3974123-A Dyes for thermoplastics BASF AKTIENGESELLSCHAFT (DT) 1976-08-10 US disclosed
US-3956264-A Basic azo dyestuffs having indolyl-methyleneamino substituent in the diazo component BAYER AKTIENGESELLSCHAFT (DT) 1976-05-11 US disclosed
US-3950321-A POLYESTERS BASF AKTIENGESELLSCHAFT (DT) 1976-04-13 US disclosed
US-3934019-A FUNGICIDE, INSECTICIDE, MITICIDE BAYER AKTIENGESELLSCHAFT (DT) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100009081-A1 3-{[4-(2-Chloro-4-nitrophenylazo)-phenyl]-ethyl-amino}-2-methyl-propionic acid vinyl ester; ink jet printing; dyeing and printing of synthetic textile material and fiber blends; dyeings on polyester with improved washfastness properties obtained if dyestuffs contain a vinyl ester group in coupling WDR77, PRMT7, CBR3 ALDH1A1 929/4885CYP3A4 128/4885GAA 4874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.