Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 5/20 | 0.32 |
| ▸ | CLK2 | P49760 | 5/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17257156 | 1.00 | HTT (0.35) | HTTALDH1A1KDM4EGLAGAA | |
| SCHEMBL17256872 | 0.88 | HTT (0.35) | HTTALDH1A1KDM4EGLAGAA | |
| SCHEMBL20384869 | 0.88 | HTT (0.35) | HTTALDH1A1KDM4EGLAGAA | |
| SCHEMBL17256797 | 0.85 | HTT (0.33) | HTTALDH1A1SMN1; SMN2NCOA3MEN1 | |
| SCHEMBL17256795 | 0.85 | HTT (0.33) | HTTALDH1A1SMN1; SMN2NCOA3MEN1 | |
| SCHEMBL17256799 | 0.84 | KDM4E (0.35) | HTTALDH1A1KDM4EGLAGAA | |
| SCHEMBL17256801 | 0.84 | KDM4E (0.35) | HTTALDH1A1KDM4EGLAGAA | |
| SCHEMBL17257281 | 0.79 | SMN1; SMN2 (0.34) | HTTALDH1A1SMN1; SMN2NCOA3CYP1A2 | |
| SCHEMBL17257284 | 0.79 | SMN1; SMN2 (0.34) | HTTALDH1A1SMN1; SMN2NCOA3CYP1A2 | |
| SCHEMBL17256968 | 0.78 | L3MBTL1 (0.51) | HTTALDH1A1GAASMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10030083-B2 | Polymers functionalized with protected oxime compounds containing a cyano group | BRIDGESTONE CORPORATION (JP) | 2018-07-24 | — | — | US | claimed |
| US-20150329655-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS CONTAINING A CYANO GROUP | BRIDGESTONE CORPORATION (JP) | 2015-11-19 | — | — | US | claimed |
| EP-3143055-B1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS CONTAINING A CYANO GROUP | BRIDGESTONE CORP (JP) | 2019-09-04 | — | — | EP | disclosed |
| US-10030083-B2 | Polymers functionalized with protected oxime compounds containing a cyano group | BRIDGESTONE CORPORATION (JP) | 2018-07-24 | — | — | US | disclosed |
| US-20150329655-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS CONTAINING A CYANO GROUP | BRIDGESTONE CORPORATION (JP) | 2015-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10030083-B2 | Polymers functionalized with protected oxime compounds containing a cyano group | PAM, PPOX, MB | HTT 3188/4885ALDH1A1 3041/4885KDM4E 1669/4885 |
| US-20150329655-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS CONTAINING A CYANO GROUP | PAM, PPOX, MB | HTT 3188/4885ALDH1A1 3041/4885KDM4E 1669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.