Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL170879 | 0.84 | TAAR1 (0.45) | TAAR1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL26562290 | 0.83 | KDM4E (0.39) | TAAR1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL301088 | 0.78 | ALDH1A1 (0.36) | KDM4EALDH1A1GAAHPGDDAO | |
| SCHEMBL172522 | 0.77 | NOS2 (0.41) | TAAR1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL170728 | 0.77 | ACHE (0.46) | TAAR1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL13228082 | 0.75 | TAAR1 (0.68) | TAAR1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL15302783 | 0.75 | TAAR1 (0.38) | TAAR1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL9189975 | 0.75 | TAAR1 (0.42) | TAAR1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL7706281 | 0.75 | TAAR1 (0.38) | TAAR1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL15618222 | 0.75 | ALDH1A1 (0.41) | TAAR1KDM4ESMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |