SCHEMBL17257510

SCHEMBL17257510

CCCCCCCCCCCCCCCC(C)C(C)(C)N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.48
SPHK1 Q9NYA1 2/20 0.45
LMNA P02545 2/20 0.39
TP53 P04637 2/20 0.39
DNM1 Q05193 2/20 0.39
TSHR P16473 1/20 0.38
THRB P10828 1/20 0.38
CYP2D6 P10635 2/20 0.38
ADH1B P00325 1/20 0.38
ADH1C P00326 1/20 0.38
ADH1A P07327 1/20 0.38
ADH4 P08319 1/20 0.38
ADH7 P40394 1/20 0.38
PLA2G1B P04054 1/20 0.38
PLA2G2A P14555 1/20 0.38
GMNN O75496 1/20 0.38
POLB P06746 1/20 0.38
THPO P40225 1/20 0.38
MTOR P42345 1/20 0.38
BLM P54132 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8385121 1.00 OPRM1 (0.48) OPRM1SPHK1LMNATP53DNM1
SCHEMBL8385082 1.00 OPRM1 (0.48) OPRM1SPHK1LMNATP53DNM1
SCHEMBL331199 1.00 OPRM1 (0.48) OPRM1SPHK1LMNATP53DNM1
SCHEMBL924201 1.00 OPRM1 (0.48) OPRM1SPHK1LMNATP53DNM1
SCHEMBL8386214 1.00 OPRM1 (0.48) OPRM1SPHK1LMNATP53DNM1
SCHEMBL332857 1.00 OPRM1 (0.48) OPRM1SPHK1LMNATP53DNM1
SCHEMBL8383457 1.00 OPRM1 (0.48) OPRM1SPHK1LMNATP53DNM1
SCHEMBL125359 1.00 OPRM1 (0.48) OPRM1SPHK1LMNATP53DNM1
SCHEMBL37786 1.00 OPRM1 (0.48) OPRM1SPHK1LMNATP53DNM1
SCHEMBL2266510 1.00 OPRM1 (0.48) OPRM1SPHK1LMNATP53DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160362448-A1 METHODS FOR REDUCING CHROMATIN CONTENT IN PROTEIN PREPARATIONS BY TREATMENT WITH ALKYL CATIONS AGENCY SCIENCE TECH & RES (SG) 2016-12-15 US claimed
CN-106061992-A Methods for reducing chromatin content in protein preparations by treatment with alkyl cations 新加坡科技研究局 2016-10-26 CN claimed
US-10113049-B2 Thermoplastic resin composition NIPPON NYUKAZAI CO., LTD. (JP) 2018-10-30 US disclosed
CN-106061992-A Methods for reducing chromatin content in protein preparations by treatment with alkyl cations 新加坡科技研究局 2016-10-26 CN disclosed
US-20150329698-A1 THERMOPLASTIC RESIN COMPOSITION NIPPON NYUKAZAI CO., LTD. (JP) 2015-11-19 US disclosed