SCHEMBL37786

SCHEMBL37786

CCCCCCCCCCCCCCCCCCC(C)C(C)(C)N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.48
SPHK1 Q9NYA1 2/20 0.45
LMNA P02545 2/20 0.39
TP53 P04637 2/20 0.39
DNM1 Q05193 2/20 0.39
TSHR P16473 1/20 0.38
THRB P10828 1/20 0.38
CYP2D6 P10635 2/20 0.38
ADH1B P00325 1/20 0.38
ADH1C P00326 1/20 0.38
ADH1A P07327 1/20 0.38
ADH4 P08319 1/20 0.38
ADH7 P40394 1/20 0.38
PLA2G1B P04054 1/20 0.38
PLA2G2A P14555 1/20 0.38
GMNN O75496 1/20 0.38
POLB P06746 1/20 0.38
THPO P40225 1/20 0.38
MTOR P42345 1/20 0.38
BLM P54132 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8385121 1.00 OPRM1 (0.48) OPRM1SPHK1LMNATP53DNM1
SCHEMBL8385082 1.00 OPRM1 (0.48) OPRM1SPHK1LMNATP53DNM1
SCHEMBL331199 1.00 OPRM1 (0.48) OPRM1SPHK1LMNATP53DNM1
SCHEMBL924201 1.00 OPRM1 (0.48) OPRM1SPHK1LMNATP53DNM1
SCHEMBL8386214 1.00 OPRM1 (0.48) OPRM1SPHK1LMNATP53DNM1
SCHEMBL332857 1.00 OPRM1 (0.48) OPRM1SPHK1LMNATP53DNM1
SCHEMBL8383457 1.00 OPRM1 (0.48) OPRM1SPHK1LMNATP53DNM1
SCHEMBL125359 1.00 OPRM1 (0.48) OPRM1SPHK1LMNATP53DNM1
SCHEMBL17257510 1.00 OPRM1 (0.48) OPRM1SPHK1LMNATP53DNM1
SCHEMBL2266510 1.00 OPRM1 (0.48) OPRM1SPHK1LMNATP53DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110269029-A1 DIRECT ALCOHOL ANION FUEL CELL WITH BIOCATHODE AKERMIN, INC. (US) 2011-11-03 US claimed
EP-2362809-A2 PROCESS FOR ACCELERATED CAPTURE OF CARBON DIOXIDE Akermin, Inc. (US) 2011-09-07 EP claimed
US-20100209968-A1 IMMOBILIZED ENZYMES AND USES THEREOF AKERMIN, INC. (US) 2010-08-19 US claimed
JP-2010516017-A 2010-05-13 JP claimed
WO-2010037109-A2 PROCESS FOR ACCELERATED CAPTURE OF CARBON DIOXIDE AKERMIN, INC. (US) 2010-04-01 WO claimed
WO-2010037138-A2 DIRECT ALCOHOL ANION FUEL CELL WITH BIOCATHODE AKERMIN, INC. (US) 2010-04-01 WO claimed
CN-101689638-A immobilized enzymes and uses thereof AKERMIN INC 2010-03-31 CN claimed
EP-2158627-A2 IMMOBILIZED ENZYMES AND USES THEREOF Akermin, Inc. (US) 2010-03-03 EP claimed
EP-2080243-A2 BIOANODE AND BIOCATHODE STACK ASSEMBLIES Akermin, Inc. (US) 2009-07-22 EP claimed
WO-2008137846-A2 IMMOBILIZED ENZYMES AND USES THEREOF AKERMIN, INC. (US) 2008-11-13 WO claimed
WO-2008058165-A2 BIOANODE AND BIOCATHODE STACK ASSEMBLIES AKERMIN, INC. (US) 2008-05-15 WO claimed
US-4225498-A Preparation of N-substituted oligo-imides RHONE-POULENC INDUSTRIES (FR) 1980-09-30 US claimed
CN-112771117-B Method for manufacturing stretched body, plastic bottle and container 三菱瓦斯化学株式会社 2023-06-02 CN disclosed
WO-2022058064-A1 AGENT FOR DECOLORIZING KERATIN MATERIAL WHICH HAS BEEN DYED USING AN ORGANOSILICON COMPOUND AND A PIGMENT HENKEL AG & CO. KGAA (DE) 2022-03-24 WO disclosed
US-11077038-B2 Cosmetic shampoos with low water content in a pouch HENKEL AG & CO. KGAA (DE) 2021-08-03 US disclosed
US-11077034-B2 Care conditioner with a low water content in a pouch HENKEL AG & CO. KGAA (DE) 2021-08-03 US disclosed
EP-0707489-A4 ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF SCOTGEN BIOPHARMACEUTICALS INC (US) 1998-07-29 EP disclosed
EP-0707489-A1 ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF Scotgen Biopharmaceuticals, Inc. (US) 1996-04-24 EP disclosed
WO-1994025053-A1 ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF SCOTGEN BIOPHARMACEUTICALS, INC. (US) 1994-11-10 WO disclosed
US-4225498-A Preparation of N-substituted oligo-imides RHONE-POULENC INDUSTRIES (FR) 1980-09-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11077038-B2 Cosmetic shampoos with low water content in a pouch KRT18, POLR1C, CUTA OPRM1 4706/4885SPHK1 3593/4885LMNA 1128/4885
US-11077034-B2 Care conditioner with a low water content in a pouch KRT18, CUTA, HACD2 OPRM1 4733/4885SPHK1 2408/4885LMNA 1360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.