Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH4 | P08319 | 1/20 | 0.38 |
| ▸ | ADH7 | P40394 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8385082 | 1.00 | OPRM1 (0.48) | OPRM1SPHK1LMNATP53DNM1 | |
| SCHEMBL331199 | 1.00 | OPRM1 (0.48) | OPRM1SPHK1LMNATP53DNM1 | |
| SCHEMBL924201 | 1.00 | OPRM1 (0.48) | OPRM1SPHK1LMNATP53DNM1 | |
| SCHEMBL8386214 | 1.00 | OPRM1 (0.48) | OPRM1SPHK1LMNATP53DNM1 | |
| SCHEMBL332857 | 1.00 | OPRM1 (0.48) | OPRM1SPHK1LMNATP53DNM1 | |
| SCHEMBL8383457 | 1.00 | OPRM1 (0.48) | OPRM1SPHK1LMNATP53DNM1 | |
| SCHEMBL125359 | 1.00 | OPRM1 (0.48) | OPRM1SPHK1LMNATP53DNM1 | |
| SCHEMBL17257510 | 1.00 | OPRM1 (0.48) | OPRM1SPHK1LMNATP53DNM1 | |
| SCHEMBL37786 | 1.00 | OPRM1 (0.48) | OPRM1SPHK1LMNATP53DNM1 | |
| SCHEMBL2266510 | 1.00 | OPRM1 (0.48) | OPRM1SPHK1LMNATP53DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707489-A4 | ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF | SCOTGEN BIOPHARMACEUTICALS INC (US) | 1998-07-29 | — | — | EP | claimed |
| EP-0707489-A1 | ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF | Scotgen Biopharmaceuticals, Inc. (US) | 1996-04-24 | — | — | EP | claimed |
| WO-1994025053-A1 | ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF | SCOTGEN BIOPHARMACEUTICALS, INC. (US) | 1994-11-10 | — | — | WO | claimed |
| US-5955584-A | NON-PROTEIN ANTIGEN COMPOSED OF STEROID COMPONENT WITH 3 BETA HYDROXY OR 3 KETO GROUP AND QUATERNARY AMMONIUM SALT; FOR THERAPY AND IMMUNOASSAY DIAGNOSIS | CHARTER VENTURES (US) | 1999-09-21 | — | — | US | disclosed |
| US-5811248-A | Atherosclerotic plaque specific antigens, antibodies thereto, and uses thereof | CHARTER VENTURES (US) | 1998-09-22 | — | — | US | disclosed |