Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17257541 | 1.00 | NPC1 (0.39) | NPC1RAB9AGAASMN1; SMN2G6PC1 | |
| SCHEMBL17257223 | 0.97 | G6PC1 (0.41) | NPC1RAB9AGAASMN1; SMN2G6PC1 | |
| SCHEMBL17257222 | 0.97 | G6PC1 (0.41) | NPC1RAB9AGAASMN1; SMN2G6PC1 | |
| SCHEMBL17257481 | 0.90 | NPC1 (0.39) | NPC1RAB9AGAASMN1; SMN2G6PC1 | |
| SCHEMBL17257480 | 0.90 | NPC1 (0.39) | NPC1RAB9AGAASMN1; SMN2G6PC1 | |
| SCHEMBL17257050 | 0.86 | G6PC1 (0.40) | NPC1RAB9AGAASMN1; SMN2G6PC1 | |
| SCHEMBL17257053 | 0.86 | G6PC1 (0.40) | NPC1RAB9AGAASMN1; SMN2G6PC1 | |
| SCHEMBL4801137 | 0.83 | G6PC1 (0.42) | NPC1RAB9AGAASMN1; SMN2G6PC1 | |
| SCHEMBL2475785 | 0.83 | G6PC1 (0.42) | NPC1RAB9AGAASMN1; SMN2G6PC1 | |
| SCHEMBL17257282 | 0.77 | G6PC1 (0.30) | G6PC1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10030083-B2 | Polymers functionalized with protected oxime compounds containing a cyano group | BRIDGESTONE CORPORATION (JP) | 2018-07-24 | — | — | US | claimed |
| US-20150329655-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS CONTAINING A CYANO GROUP | BRIDGESTONE CORPORATION (JP) | 2015-11-19 | — | — | US | claimed |
| EP-3143055-B1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS CONTAINING A CYANO GROUP | BRIDGESTONE CORP (JP) | 2019-09-04 | — | — | EP | disclosed |
| US-10030083-B2 | Polymers functionalized with protected oxime compounds containing a cyano group | BRIDGESTONE CORPORATION (JP) | 2018-07-24 | — | — | US | disclosed |
| EP-3143055-A2 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS CONTAINING A CYANO GROUP | Bridgestone Corporation (JP) | 2017-03-22 | — | — | EP | disclosed |
| US-20150329655-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS CONTAINING A CYANO GROUP | BRIDGESTONE CORPORATION (JP) | 2015-11-19 | — | — | US | disclosed |
| WO-2015175280-A2 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS CONTAINING A CYANO GROUP | BRIDGESTONE CORPORATION (JP) | 2015-11-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10030083-B2 | Polymers functionalized with protected oxime compounds containing a cyano group | PAM, PPOX, MB | NPC1 4775/4885RAB9A 4587/4885GAA 2104/4885 |
| US-20150329655-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS CONTAINING A CYANO GROUP | PAM, PPOX, MB | NPC1 4775/4885RAB9A 4587/4885GAA 2104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.