Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | SLC34A1 | Q06495 | 4/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1725607 | 0.76 | MAPT (0.49) | PGRNR3C2ADORA2AGRM5SLC34A1 | |
| SCHEMBL21711408 | 0.71 | GRM5 (0.48) | PGRNR3C2ADORA2AADORA2BADORA1 | |
| SCHEMBL9997510 | 0.70 | SLC34A1 (0.42) | PGRNR3C2PDE10ASLC34A1MAPK14 | |
| SCHEMBL20698315 | 0.69 | GRM4 (0.39) | SLC34A1 | |
| SCHEMBL19248544 | 0.69 | ALDH1A1 (0.46) | ADORA1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL30786508 | 0.69 | PTGS2 (0.46) | — | |
| SCHEMBL3488435 | 0.68 | PGR (0.45) | PGRNR3C2ADORA2AGRM5SLC34A1 | |
| SCHEMBL20697939 | 0.68 | MAPK1 (0.41) | PGRNR3C2ADORA2AADORA1SLC34A1 | |
| SCHEMBL21711491 | 0.67 | SLC34A1 (0.47) | PGRNR3C2ADORA2AADORA2BADORA1 | |
| SCHEMBL20698316 | 0.67 | GRM4 (0.39) | SLC34A1ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403834-A1 | Fungicidal pyrazoles | E. I. du Pont de Nemours and Company (US) | 2012-01-11 | — | — | EP | disclosed |