SCHEMBL1725975

SCHEMBL1725975

CCCCP(=O)(CCC)CCC

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
TRPM8 Q7Z2W7 7/20 0.48
GABBR2 O75899 1/20 0.48
GABRR1 P24046 1/20 0.48
GABBR1 Q9UBS5 1/20 0.48
CYP3A4 P08684 1/20 0.43
LPAR3 Q9UBY5 3/20 0.42
LPAR2 Q9HBW0 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11889581 1.00 HPGD (0.52) HPGDSMN1; SMN2TRPM8GABBR2GABRR1
SCHEMBL1726162 1.00 HPGD (0.52) HPGDSMN1; SMN2TRPM8GABBR2GABRR1
SCHEMBL152127 0.94 HPGD (0.56) HPGDSMN1; SMN2TRPM8GABBR2GABRR1
SCHEMBL11521300 0.92 LPAR3 (0.54) HPGDSMN1; SMN2TRPM8GABBR2GABRR1
Water SCHEMBL32685216 0.90 HPGD (0.54) HPGDSMN1; SMN2TRPM8GABBR2GABRR1
SCHEMBL10426422 0.90 TRPM8 (0.44) HPGDSMN1; SMN2TRPM8GABBR2GABRR1
SCHEMBL575635 0.88 HPGD (0.48) HPGDSMN1; SMN2TRPM8GABBR2GABRR1
SCHEMBL409091 0.88 LPAR3 (0.56) TRPM8LPAR3LPAR2TSHR
SCHEMBL1725977 0.88 TRPM8 (0.61) HPGDSMN1; SMN2TRPM8GABBR2GABRR1
SCHEMBL10556882 0.88 TRPM8 (0.61) HPGDSMN1; SMN2TRPM8GABBR2GABRR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2403642-B1 METHODS OF USING A SELECTIVE HYDROGENATION CATALYST CHEVRON PHILLIPS CHEMICAL CO LP (US) 2017-08-02 EP claimed
EP-3144064-B1 SELECTIVE HYDROGENATION CATALYST AND METHODS OF MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL CO LP (US) 2021-07-28 EP disclosed
EP-3377596-A1 SELECTIVE HYDROGENATION USING A FLOW INDEX Chevron Phillips Chemical Company LP (US) 2018-09-26 EP disclosed
CN-108291157-A Selective hydrogenation using flow index 切弗朗菲利浦化学公司 2018-07-17 CN disclosed
US-20180148260-A1 Selective Hydrogenation Using a Flow Index CHEVRON PHILLIPS CHEMICAL COMPANY LP 2018-05-31 US disclosed
US-9914676-B2 Selective hydrogenation using a flow index CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2018-03-13 US disclosed
US-20170349507-A1 Selective Hydrogenation Using a Flow Index CHEVRON PHILLIPS CHEMICAL COMPANY LP 2017-12-07 US disclosed
EP-3218104-A1 SELECTIVE HYDROGENATION CATALYST AND METHODS OF MAKING AND USING SAME Chevron Phillips Chemical Company LP (US) 2017-09-20 EP disclosed
US-9758446-B2 Selective hydrogenation using a flow index CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2017-09-12 US disclosed
CN-107107049-A Selective hydrogenation catalyst and its preparation and application 切弗朗菲利浦化学公司 2017-08-29 CN disclosed
CN-103608322-A Production of hydroxy ether hydrocarbons by vapor phase hydrogenolysis of cyclic acetals and ketals EASTMAN CHEM CO 2014-02-26 CN disclosed
US-8633127-B2 Selective hydrogenation catalyst and methods of making and using same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2014-01-21 US disclosed
WO-2012177484-A1 CATALYSTS FOR THE PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY VAPOR PHASE HYDROGENOLYSIS OF CYCLIC ACETALS AND KETALS EASTMAN CHEMICAL COMPANY (US) 2012-12-27 WO disclosed
WO-2012177602-A1 PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY VAPOR PHASE HYDROGENOLYSIS OF CYCLIC ACETALS AND KETALS EASTMAN CHEMICAL COMPANY (US) 2012-12-27 WO disclosed
US-20120330066-A1 PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY VAPOR PHASE HYDROGENOLYSIS OF CYCLIC ACETALS AND KETALS EASTMAN CHEMICAL COMPANY (US) 2012-12-27 US disclosed
US-20120330067-A1 CATALYSTS FOR THE PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY VAPOR PHASE HYDROGENOLYSIS OF CYCLIC ACETALS AND KETALS EASTMAN CHEMICAL COMPANY (US) 2012-12-27 US disclosed
CN-102341175-A Selective hydrogenation catalyst and methods of making and using same CHEVRON PHILLIPS CHEMICAL CO 2012-02-01 CN disclosed
EP-2403642-A2 SELECTIVE HYDROGENATION CATALYST AND METHODS OF MAKING AND USING SAME Chevron Phillips Chemical Company LP (US) 2012-01-11 EP disclosed
WO-2010101736-A2 SELECTIVE HYDROGENATION CATALYST AND METHODS OF MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2010-09-10 WO disclosed
US-20100228065-A1 Selective Hydrogenation Catalyst and Methods of Making and Using Same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2010-09-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120330067-A1 CATALYSTS FOR THE PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY VAPOR PHASE HYDROGENOLYSIS OF CYCLIC ACETALS AND KETALS SUV39H2, KAT5, SUV39H1 HPGD 948/4885SMN1; SMN2 2820/4885TRPM8 2396/4885
US-20120330066-A1 PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY VAPOR PHASE HYDROGENOLYSIS OF CYCLIC ACETALS AND KETALS SUV39H1, HDHD5, SUV39H2 HPGD 141/4885SMN1; SMN2 4014/4885TRPM8 3150/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.