Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 7/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10424958 | 0.91 | TRPM8 (0.39) | TRPM8L3MBTL1HPGDSMN1; SMN2CYP3A4 | |
| SCHEMBL1726162 | 0.90 | HPGD (0.52) | TRPM8L3MBTL1HPGDSMN1; SMN2CYP3A4 | |
| SCHEMBL1725975 | 0.90 | HPGD (0.52) | TRPM8L3MBTL1HPGDSMN1; SMN2CYP3A4 | |
| SCHEMBL11889581 | 0.90 | HPGD (0.52) | TRPM8L3MBTL1HPGDSMN1; SMN2CYP3A4 | |
| SCHEMBL563253 | 0.89 | L3MBTL1 (0.48) | TRPM8L3MBTL1HPGDSMN1; SMN2GABBR2 | |
| SCHEMBL409091 | 0.85 | LPAR3 (0.56) | TRPM8LPAR3LPAR2 | |
| SCHEMBL3017433 | 0.83 | ALDH1A1 (0.43) | TRPM8L3MBTL1HPGDSMN1; SMN2GABBR2 | |
| SCHEMBL9617461 | 0.83 | GABBR2 (0.60) | CYP3A4GABBR2GABBR1GABRR1 | |
| SCHEMBL11521300 | 0.83 | LPAR3 (0.54) | TRPM8HPGDSMN1; SMN2GABBR2GABBR1 | |
| SCHEMBL152127 | 0.83 | HPGD (0.56) | TRPM8HPGDSMN1; SMN2CYP3A4GABBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4902833-A | Bisphosphine dioxides | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) | 1990-02-20 | — | — | US | disclosed |