Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1725501 | 0.81 | TSHR (0.39) | TSHRTP53ALDH1A1KDM4EGAA | |
| SCHEMBL11303251 | 0.74 | TSHR (0.33) | TSHRALDH1A1 | |
| SCHEMBL3151180 | 0.72 | ALDH1A1 (0.38) | TSHRTP53ALDH1A1KDM4EGAA | |
| SCHEMBL10885490 | 0.70 | ALDH1A1 (0.36) | TSHRTP53ALDH1A1KDM4EGAA | |
| SCHEMBL10891280 | 0.70 | TSHR (0.36) | TSHRTP53ALDH1A1KDM4EGAA | |
| SCHEMBL11051483 | 0.69 | TSHR (0.39) | TSHRTP53ALDH1A1KDM4EGAA | |
| SCHEMBL27496531 | 0.69 | ALDH1A1 (0.37) | TSHRTP53ALDH1A1KDM4EGAA | |
| SCHEMBL9798347 | 0.68 | GAA (0.37) | TSHRTP53ALDH1A1KDM4EGAA | |
| SCHEMBL11524279 | 0.66 | ALDH1A1 (0.39) | TSHRTP53ALDH1A1KDM4EGAA | |
| SCHEMBL4033195 | 0.65 | CYP3A4 (0.39) | TSHRTP53ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2370207-A1 | HYDROGENATION OF ESTER, KETONE OR ALDEHYDE GROUPS WITH RUTHENIUM COMPLEXES HAVING A DI-AMINE AND A PHOSPHOROUS-NITROGEN BIDENTATE LIGAND | Firmenich S.A. (CH) | 2011-10-05 | — | — | EP | disclosed |
| US-20110190523-A1 | HYDROGENATION OF ESTERS OR CARBONYL GROUPS WITH PHOSPHINO-OXIDE BASED RUTHENIUM COMPLEXES | FIRMENICH SA (CH) | 2011-08-04 | — | — | US | disclosed |
| EP-2344276-A1 | HYDROGENATION OF ESTERS OR CARBONYL GROUPS WITH PHOSPHINO-OXIDE BASED RUTHENIUM COMPLEXES | Firmenich S.A. (CH) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010061350-A1 | HYDROGENATION OF ESTER, KETONE OR ALDEHYDE GROUPS WITH RUTHENIUM COMPLEXES HAVING A DI-AMINE AND A PHOSPHOROUS-NITROGEN BIDENTATE LIGAND | FIRMENICH SA (CH) | 2010-06-03 | — | — | WO | disclosed |
| WO-2010038209-A1 | HYDROGENATION OF ESTERS OR CARBONYL GROUPS WITH PHOSPHINO-OXIDE BASED RUTHENIUM COMPLEXES | FIRMENICH SA (CH) | 2010-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190523-A1 | HYDROGENATION OF ESTERS OR CARBONYL GROUPS WITH PHOSPHINO-OXIDE BASED RUTHENIUM COMPLEXES | PNN, ADH5, NCL | TSHR 3223/4885TP53 919/4885ALDH1A1 897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.