SCHEMBL9798347

SCHEMBL9798347

C=CCOC(=O)C1C(=C)CCCC1(C)C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.37
RECQL P46063 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TRPA1 O75762 2/20 0.35
TP53 P04637 3/20 0.35
TSHR P16473 2/20 0.35
ALDH1A1 P00352 3/20 0.34
KDM4E B2RXH2 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CYP3A4 P08684 2/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
PTPN2 P17706 2/20 0.33
PTPN1 P18031 2/20 0.33
TRPC6 Q9Y210 3/20 0.32
NR3C1 P04150 3/20 0.32
PGR P06401 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL814348 0.84 ALDH1A1 (0.38) GAATRPA1TP53ALDH1A1KDM4E
SCHEMBL9798207 0.81 TRPA1 (0.36) SMN1; SMN2TRPA1ALDH1A1MEN1LMNA
SCHEMBL23530425 0.79 TRPA1 (0.39) GAASMN1; SMN2TRPA1TSHRALDH1A1
SCHEMBL29414123 0.79 TRPA1 (0.39) GAASMN1; SMN2TRPA1TSHRALDH1A1
SCHEMBL755859 0.79 TRPA1 (0.39) GAASMN1; SMN2TRPA1TSHRALDH1A1
SCHEMBL9837114 0.78 TRPA1 (0.35) TRPA1TP53CYP3A4MEN1LMNA
SCHEMBL9798127 0.78 TRPA1 (0.37) TRPA1TP53CYP3A4PTPN2PTPN1
SCHEMBL10885490 0.77 ALDH1A1 (0.36) GAARECQLSMN1; SMN2TP53TSHR
Ethyl Acetate SCHEMBL28147899 0.74 TRPA1 (0.38) SMN1; SMN2TRPA1TP53TSHRALDH1A1
SCHEMBL4359741 0.73 TRPA1 (0.41) TRPA1TP53ALDH1A1CYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5015625-A Methylenecyclohexane Carboxylates FIRMENICH SA (CH) 1991-05-14 US disclosed