Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | FKBP1A | P62942 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19818799 | 0.94 | L3MBTL1 (0.64) | L3MBTL1POLBLMNASMN1; SMN2FKBP1A | |
| SCHEMBL30643718 | 0.84 | L3MBTL1 (0.52) | L3MBTL1POLBLMNASMN1; SMN2TSHR | |
| SCHEMBL12439630 | 0.82 | L3MBTL1 (0.78) | L3MBTL1POLBLMNASMN1; SMN2FKBP1A | |
| SCHEMBL14654219 | 0.81 | L3MBTL1 (0.70) | L3MBTL1POLBLMNASMN1; SMN2FKBP1A | |
| SCHEMBL9633223 | 0.80 | L3MBTL1 (0.51) | L3MBTL1POLBLMNASMN1; SMN2HTT | |
| SCHEMBL9124397 | 0.79 | L3MBTL1 (0.72) | L3MBTL1POLBLMNASMN1; SMN2FKBP1A | |
| SCHEMBL29307070 | 0.79 | L3MBTL1 (0.43) | L3MBTL1POLBSMN1; SMN2NPC1TSHR | |
| SCHEMBL12542224 | 0.78 | POLB (0.51) | L3MBTL1POLBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL15040863 | 0.78 | MEN1 (0.55) | L3MBTL1POLBLMNASMN1; SMN2NPC1 | |
| SCHEMBL253804 | 0.77 | GLA (0.64) | L3MBTL1POLBLMNASMN1; SMN2FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170190684-A1 | PREPARATION METHOD FOR CHIRAL INTERMEDIATE FOR USE IN STATINS | ASYMCHEM LABORATORIES (TIANJIN) CO., LTD. (CN) | 2017-07-06 | — | — | US | disclosed |
| EP-3141544-A1 | PREPARATION METHOD FOR CHIRAL INTERMEDIATE FOR USE IN STATINS | Asymchem Laboratories (Tianjin) Co., Ltd (CN) | 2017-03-15 | — | — | EP | disclosed |
| EP-2403846-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | F. Hoffmann-La Roche AG (CH) | 2012-01-11 | — | — | EP | disclosed |
| WO-2010100070-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | F. HOFFMANN-LA ROCHE AG (CH) | 2010-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190684-A1 | PREPARATION METHOD FOR CHIRAL INTERMEDIATE FOR USE IN STATINS | HMGCR, COASY, CETP | L3MBTL1 4275/4885POLB 739/4885LMNA 760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.