Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23484812 | 0.85 | GNAI3 (0.51) | L3MBTL1GNAI3GNAO1GNAI1TDP1 | |
| SCHEMBL30643718 | 0.83 | L3MBTL1 (0.52) | L3MBTL1POLBGNAI3GNAO1GNAI1 | |
| SCHEMBL15934102 | 0.81 | GAA (0.46) | L3MBTL1POLBTP53TDP1KDM4E | |
| SCHEMBL24675781 | 0.81 | GNAI3 (0.58) | L3MBTL1GNAI3GNAO1GNAI1TDP1 | |
| SCHEMBL24674880 | 0.81 | ALDH1A1 (0.39) | L3MBTL1POLBTDP1ALDH1A1GAA | |
| SCHEMBL13251295 | 0.79 | ALDH1A1 (0.54) | L3MBTL1POLBTP53TDP1ALDH1A1 | |
| SCHEMBL1726021 | 0.79 | L3MBTL1 (0.68) | L3MBTL1POLBTSHRALDH1A1NPC1 | |
| SCHEMBL9122963 | 0.78 | L3MBTL1 (0.43) | L3MBTL1POLBTP53TDP1ALDH1A1 | |
| SCHEMBL27400094 | 0.77 | GNAI3 (0.42) | L3MBTL1GNAI3GNAO1GNAI1TDP1 | |
| SCHEMBL12542224 | 0.76 | POLB (0.51) | L3MBTL1POLBGNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148060-A1 | MK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |