Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.39 |
| ▸ | ACSS2 | Q9NR19 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6090949 | 0.82 | CYP19A1 (0.64) | CYP19A1CFTRGOPCKMT2ACYP3A4 | |
| SCHEMBL11532100 | 0.77 | CYP19A1 (0.62) | CYP19A1CFTRGOPCKMT2ACYP3A4 | |
| SCHEMBL11535538 | 0.74 | CYP19A1 (0.51) | CYP19A1CFTRGOPCKMT2ACYP3A4 | |
| SCHEMBL11534840 | 0.74 | CYP19A1 (0.88) | CYP19A1CYP3A4 | |
| SCHEMBL11535325 | 0.74 | CYP19A1 (0.62) | CYP19A1CFTRGOPCKMT2ATAAR1 | |
| SCHEMBL11533232 | 0.74 | CYP19A1 (0.62) | CYP19A1CFTRGOPCKMT2ACYP3A4 | |
| SCHEMBL11537316 | 0.74 | CYP19A1 (0.62) | CYP19A1CFTRGOPCKMT2AF2RL1 | |
| SCHEMBL11631351 | 0.73 | NISCH (0.39) | CFTRGOPCACSS2KMT2ACYP3A4 | |
| SCHEMBL6302051 | 0.72 | CYP19A1 (0.47) | CYP19A1CFTRGOPCKMT2ACYP3A4 | |
| SCHEMBL697087 | 0.72 | CYP19A1 (0.47) | CYP19A1CFTRGOPCKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015175845-A1 | BENZIMIDAZOLE DERIVATIVES AND USES THEREOF | PELOTON THERAPEUTICS, INC. (US) | 2015-11-19 | — | — | WO | disclosed |