SCHEMBL17263271

SCHEMBL17263271

COC(=O)c1nccnc1-c1ccccc1C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.45
SMN1; SMN2 Q16637 1/20 0.41
TDP2 O95551 1/20 0.40
KDM4E B2RXH2 4/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 1/20 0.40
KMT2A Q03164 1/20 0.39
FGFR1 P11362 1/20 0.39
FGFR2 P21802 1/20 0.39
FGFR4 P22455 1/20 0.39
FGFR3 P22607 1/20 0.39
STAT3 P40763 1/20 0.39
HIF1A Q16665 1/20 0.39
PIK3CD O00329 3/20 0.38
TSHR P16473 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
IDO1 P14902 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3398695 0.82 KDM4E (0.44) L3MBTL1KDM4EMAPTKMT2APIK3CD
SCHEMBL30775035 0.81 L3MBTL1 (0.53) L3MBTL1TDP2KDM4EPOLBKMT2A
SCHEMBL17263270 0.80 ALPL (0.41) L3MBTL1SMN1; SMN2KDM4EALDH1A1HSD17B10
SCHEMBL25245831 0.79 SMN1; SMN2 (0.59) L3MBTL1SMN1; SMN2KDM4EMAPTKMT2A
SCHEMBL30511946 0.78 SLC6A3 (0.47) L3MBTL1KDM4EPOLBMAPTKMT2A
SCHEMBL17263272 0.77 TRPV1 (0.48) L3MBTL1MAPTKMT2AALDH1A1
SCHEMBL17263284 0.77 PDK2 (0.38) L3MBTL1SMN1; SMN2TDP2KDM4EMAPT
SCHEMBL13320926 0.76 RIOK2 (0.36) L3MBTL1KDM4EMAPTKMT2A
SCHEMBL128711 0.76 L3MBTL1 (0.62) L3MBTL1SMN1; SMN2KDM4EPOLBALDH1A1
SCHEMBL31347575 0.76 L3MBTL1 (0.62) L3MBTL1SMN1; SMN2KDM4EPOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9187689-B2 Organometallic complex and light-emitting element, light-emitting device, and electronic device using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-17 US disclosed