Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 6/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15256081 | 0.88 | CRHR1 (0.48) | CRHR1CYP11B1CYP11B2NPC1 | |
| SCHEMBL17263292 | 0.80 | CRHR1 (0.44) | CRHR1CYP11B1CYP11B2NPC1ADRA2A | |
| SCHEMBL17224064 | 0.80 | CRHR1 (0.42) | CRHR1CYP11B1CYP11B2TLR8NPC1 | |
| SCHEMBL12326180 | 0.78 | CA1 (0.50) | CYP11B1CYP11B2 | |
| SCHEMBL15688357 | 0.78 | CRHR1 (0.43) | CRHR1CYP11B1CYP11B2NPC1 | |
| SCHEMBL17178245 | 0.78 | DRD1 (0.58) | CRHR1CYP11B1CYP11B2TLR8NPC1 | |
| SCHEMBL6285490 | 0.78 | CRHR1 (0.53) | CRHR1NPC1 | |
| SCHEMBL14307063 | 0.78 | KDM4E (0.54) | CRHR1CYP11B1CYP11B2 | |
| SCHEMBL15688500 | 0.77 | ADRA2A (0.44) | CRHR1CYP11B1CYP11B2ADRA2AADRA2C | |
| SCHEMBL17178283 | 0.77 | DRD1 (0.46) | CRHR1AMY1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187689-B2 | Organometallic complex and light-emitting element, light-emitting device, and electronic device using the same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2015-11-17 | — | — | US | disclosed |