Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 5/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6358187 | 0.86 | CYP1A1 (0.46) | CRHR1KDM4EALDH1A1MAPTHTT | |
| SCHEMBL17178245 | 0.85 | DRD1 (0.58) | CRHR1DRD1KDM4EALDH1A1MAPT | |
| SCHEMBL15688357 | 0.85 | CRHR1 (0.43) | CRHR1DRD1KDM4EALDH1A1MAPT | |
| SCHEMBL17263273 | 0.80 | CRHR1 (0.51) | CRHR1CYP11B1CYP11B2NPC1ADRA2A | |
| SCHEMBL20171948 | 0.80 | HSP90AB1 (0.37) | CRHR1DRD1KDM4EALDH1A1MAPT | |
| SCHEMBL15688500 | 0.79 | ADRA2A (0.44) | CRHR1DRD1KDM4EALDH1A1MAPT | |
| SCHEMBL18472059 | 0.77 | DRD1 (0.45) | CRHR1DRD1KDM4EALDH1A1MAPT | |
| SCHEMBL15256081 | 0.76 | CRHR1 (0.48) | CRHR1KDM4EALDH1A1MAPTHTT | |
| SCHEMBL28627456 | 0.75 | CLK4 (0.50) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL13320968 | 0.75 | CYP1A2 (0.42) | CRHR1KDM4EPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187689-B2 | Organometallic complex and light-emitting element, light-emitting device, and electronic device using the same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2015-11-17 | — | — | US | disclosed |