Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20171948 | 0.86 | HSP90AB1 (0.37) | JAK3HSP90AB1LMNARAB9ANPC1 | |
| SCHEMBL11438697 | 0.83 | DRD1 (0.39) | HSP90AB1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL17263290 | 0.79 | JAK3 (0.48) | JAK3LMNARAB9ANPC1MEN1 | |
| SCHEMBL17263288 | 0.77 | JAK3 (0.45) | JAK3NPC1MEN1KMT2AMAPT | |
| SCHEMBL18356854 | 0.77 | CNR2 (0.44) | HSP90AB1LMNARAB9ANPC1MEN1 | |
| SCHEMBL17263278 | 0.76 | HSP90AB1 (0.39) | HSP90AB1LMNARAB9ANPC1MEN1 | |
| SCHEMBL15256080 | 0.73 | NPC1 (0.40) | LMNARAB9ANPC1MEN1KMT2A | |
| SCHEMBL4754291 | 0.72 | JAK3 (0.44) | JAK3LMNAMAPTNPSR1ALOX15 | |
| SCHEMBL26155339 | 0.72 | CYP1A2 (0.45) | HSP90AB1LMNARAB9ANPC1MEN1 | |
| SCHEMBL22686569 | 0.71 | MAPT (0.41) | HSP90AB1LMNARAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187689-B2 | Organometallic complex and light-emitting element, light-emitting device, and electronic device using the same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2015-11-17 | — | — | US | disclosed |