SCHEMBL172637

SCHEMBL172637

CCCN(C)Cc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.67
PRMT6 Q96LA8 1/20 0.67
PRMT8 Q9NR22 1/20 0.67
SIGMAR1 Q99720 2/20 0.60
TSHR P16473 3/20 0.56
ALDH1A1 P00352 3/20 0.56
MAOB P27338 4/20 0.53
LMNA P02545 3/20 0.53
MAOA P21397 2/20 0.53
USP2 O75604 1/20 0.53
CYP3A4 P08684 1/20 0.53
PYCR1 P32322 1/20 0.53
AOC3 Q16853 1/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
BLM P54132 1/20 0.52
KDM4E B2RXH2 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL9400548 0.98 CARM1 (0.64) CARM1PRMT6PRMT8SIGMAR1TSHR
Hydrochloric Acid SCHEMBL27701533 0.98 CARM1 (0.64) CARM1PRMT6PRMT8SIGMAR1TSHR
Hydrochloric Acid SCHEMBL17710433 0.98 CARM1 (0.64) CARM1PRMT6PRMT8SIGMAR1TSHR
SCHEMBL7055109 0.88 CARM1 (0.75) CARM1PRMT6PRMT8SIGMAR1TSHR
SCHEMBL21118237 0.88 HRH3 (0.54) CARM1PRMT6PRMT8SIGMAR1TSHR
SCHEMBL18158147 0.88 CARM1 (0.58) CARM1PRMT6PRMT8SIGMAR1TSHR
SCHEMBL1638713 0.87 SIGMAR1 (0.67) CARM1PRMT6PRMT8SIGMAR1TSHR
SCHEMBL2749362 0.85 SIGMAR1 (0.70) CARM1PRMT6PRMT8SIGMAR1MAOB
SCHEMBL15790968 0.84 CARM1 (0.64) CARM1PRMT6PRMT8SIGMAR1TSHR
SCHEMBL1088446 0.84 SIGMAR1 (0.74) CARM1PRMT6PRMT8SIGMAR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109476803-B Amine compositions useful for making polyurethane foams 赢创运营有限公司 2022-04-12 CN claimed
US-10472565-B2 Low temperature activator systems and methods for chemiluminescent reactions CYALUME TECHNOLOGIES, INC. (US) 2019-11-12 US claimed
EP-3004286-B1 BROAD TEMPERATURE PERFORMANCE CHEMILUMINESCENT SYSTEMS AND METHODS CYALUME TECH INC (US) 2019-08-28 EP claimed
EP-3004286-A1 BROAD TEMPERATURE PERFORMANCE CHEMILUMINESCENT SYSTEMS AND METHODS Cyalume Technologies, Inc (US) 2016-04-13 EP claimed
CN-105001154-A Method for synthesizing 2-halogenated nicotinate and intermediate thereof through ionic liquid method UNIV SHANDONG NORMAL 2015-10-28 CN claimed
US-9115305-B2 Broad temperature performance chemiluminescent systems and methods CYALUME TECHNOLOGIES, INC. (US) 2015-08-25 US claimed
US-20140353559-A1 BROAD TEMPERATURE PERFORMANCE CHEMILUMINESCENT SYSTEMS AND METHODS Cyalume Technologies (US) 2014-12-04 US claimed
WO-2014194332-A1 BROAD TEMPERATURE PERFORMANCE CHEMILUMINESCENT SYSTEMS AND METHODS Cyalume Technologies (US) 2014-12-04 WO claimed
US-20140356975-A1 LOW TEMPERATURE ACTIVATOR SYSTEMS AND METHODS FOR CHEMILUMINESCENT REACTIONS Cyalume Technologies (US) 2014-12-04 US claimed
US-20140283198-A1 Signaling Compositions, Methods, and Systems for Effecting Plant Growth and Crop Enhancement KamTec, LLC (US) 2014-09-18 US claimed
US-20140283199-A1 Signaling Compositions, Methods, and Systems for Effecting Plant Burndown and Herbicide Enhancement KamTec (US) 2014-09-18 US claimed
EP-4139308-B1 PURINE DERIVATIVES AS DRUGS FOR THE TREATMENT OF NEONATAL HYPOXIA-ISCHEMIA BRAIN INJURY AND RELATED DISEASES COMMISSARIAT ENERGIE ATOMIQUE (FR) 2024-07-17 EP disclosed
WO-2024128157-A1 COMPOSITION FOR FORMING RESIST UNDERLAYER FILM 日産化学株式会社 2024-06-20 WO disclosed
US-20230339902-A1 TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 C4 THERAPEUTICS, INC. (US) 2023-10-26 US disclosed
WO-2023116915-A1 ACHE/SERT DUAL-TARGET INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF 珠海市藤栢医药有限公司 2023-06-29 WO disclosed
US-4853386-A INHIBITORS OF SRS-A(SLOW REACTING SUBSTANCE OF ANAPHYLAXIS) FROM LUNG TISSUES BOEHRINGER MANNHEIM GMBH (DE) 1989-08-01 US disclosed
EP-0292564-A1 PROCESS FOR PREPARING ALKOXYALKYL-SUBSTITUTED PHENOLS IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1988-11-30 EP disclosed
US-4751223-A Antiinflammatory and analgesic aminoalkyl tetracyclic benzodiazepines HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1988-06-14 US disclosed
EP-0268793-A1 Aminoalkyl tetracyclic benzodiazepines, a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1988-06-01 EP disclosed
EP-0217142-A2 A polyazaheterocyclic compound Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1987-04-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230339902-A1 TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 IKZF1, IKZF3, IKZF2 CARM1 1864/4885PRMT6 3374/4885PRMT8 3097/4885
US-20140283199-A1 Signaling Compositions, Methods, and Systems for Effecting Plant Burndown and Herbicide Enhancement BOLA2; BOLA2B, DBNL, EBPL CARM1 1891/4885PRMT6 2654/4885PRMT8 2462/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.