Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.50 |
| ▸ | PYCR1 | P32322 | 7/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16550458 | 0.93 | KDM4E (0.53) | HRH3KDM4EALDH1A1CARM1PRMT6 | |
| SCHEMBL14006726 | 0.89 | PYCR1 (0.56) | HRH3KDM4EALDH1A1PYCR1SIGMAR1 | |
| SCHEMBL15308539 | 0.89 | PYCR1 (0.56) | HRH3KDM4EALDH1A1CARM1PRMT6 | |
| SCHEMBL3152090 | 0.89 | MAPT (0.58) | HRH3KDM4EALDH1A1CARM1PRMT6 | |
| SCHEMBL14873857 | 0.89 | KDM4E (0.50) | HRH3KDM4EALDH1A1CARM1PRMT6 | |
| SCHEMBL23601608 | 0.89 | ALDH1A1 (0.46) | HRH3KDM4EALDH1A1CARM1PRMT6 | |
| SCHEMBL4667028 | 0.89 | CARM1 (0.52) | HRH3KDM4EALDH1A1CARM1PRMT6 | |
| SCHEMBL1241978 | 0.89 | KDM4E (0.70) | HRH3KDM4EALDH1A1CARM1PRMT6 | |
| SCHEMBL172637 | 0.88 | CARM1 (0.67) | KDM4EALDH1A1CARM1PRMT6PRMT8 | |
| Hydrochloric Acid SCHEMBL17710433 | 0.86 | CARM1 (0.64) | KDM4EALDH1A1CARM1PRMT6PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190169140-A1 | IDO1 INHIBITOR AND PREPARATION METHOD AND APPLICATION THEREOF | SHANDONG LUYE PHARMACEUTICAL CO., LTD. (CN) | 2019-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190169140-A1 | IDO1 INHIBITOR AND PREPARATION METHOD AND APPLICATION THEREOF | IDO1, IDO2, INMT | HRH3 1490/4885KDM4E 986/4885ALDH1A1 304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.