SCHEMBL2749362

SCHEMBL2749362

CCCCCN(C)Cc1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ SIGMAR1 Q99720 4/20 0.70
▸ CARM1 Q86X55 1/20 0.60
▸ PRMT6 Q96LA8 1/20 0.60
▸ PRMT8 Q9NR22 1/20 0.60
▸ MAOB P27338 4/20 0.57
▸ MAOA P21397 1/20 0.57
▸ ACHE P22303 5/20 0.54
▸ LMNA P02545 1/20 0.53
▸ MEN1 O00255 1/20 0.52
▸ KMT2A Q03164 1/20 0.52
▸ TMEM97 Q5BJF2 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9131293 0.98 SIGMAR1 (0.73) SIGMAR1CARM1PRMT6PRMT8MAOB
SCHEMBL9275367 0.98 SIGMAR1 (0.73) SIGMAR1CARM1PRMT6PRMT8MAOB
SCHEMBL9274175 0.98 SIGMAR1 (0.73) SIGMAR1CARM1PRMT6PRMT8MAOB
SCHEMBL11040881 0.98 SIGMAR1 (0.73) SIGMAR1CARM1PRMT6PRMT8MAOB
SCHEMBL15966133 0.98 SIGMAR1 (0.73) SIGMAR1CARM1PRMT6PRMT8MAOB
SCHEMBL15966143 0.98 SIGMAR1 (0.73) SIGMAR1CARM1PRMT6PRMT8MAOB
SCHEMBL6366898 0.98 SIGMAR1 (0.73) SIGMAR1CARM1PRMT6PRMT8MAOB
SCHEMBL3805871 0.98 SIGMAR1 (0.73) SIGMAR1CARM1PRMT6PRMT8MAOB
SCHEMBL10773804 0.98 SIGMAR1 (0.73) SIGMAR1CARM1PRMT6PRMT8MAOB
SCHEMBL278595 0.98 SIGMAR1 (0.73) SIGMAR1CARM1PRMT6PRMT8MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112262166-A Polyurethane foam-forming compositions 速的奥公司 2021-01-22 — — CN claimed
EP-2038291-B1 PROCESS FOR THE SYNTHESIS OF IBANDRONATE SODIUM CIPLA LTD (IN) 2010-07-14 — — EP claimed
CN-120117949-A Method for directly preparing tertiary amine compound from aromatic aldehyde, ketone and secondary amine 湖南大学 2025-06-10 — — CN disclosed
CN-112262166-A Polyurethane foam-forming compositions 速的奥公司 2021-01-22 — — CN disclosed
US-20180086713-A1 CGAS IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) UNIVERSITY OF WASHINGTON 2018-03-29 — — US disclosed
US-9616099-B2 Cyclosporin analogues for preventing or treating hepatitis C infection ENANTA PHARMACEUTICALS, INC. (US) 2017-04-11 — — US disclosed
US-9573942-B2 HIV inhibiting 5-amido substituted pyrimidines JANSSEN SCIENCES IRELAND UC (IE) 2017-02-21 — — US disclosed
US-20170017153-A1 PHOTOSENSITIVE RESIN COMPOSITION, LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD FOR PRODUCING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2017-01-19 — — US disclosed
US-20160136233-A1 NOVEL CYCLOSPORIN ANALOGUES FOR PREVENTING OR TREATING HEPATITIS C INFECTION ENANTA PHARM INC (US) 2016-05-19 — — US disclosed
US-9315670-B2 Composition for forming resist underlayer film and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-04-19 — — US disclosed
US-9221878-B2 Cyclosporin analogues for preventing or treating hepatitis C infection ENANTA PHARMACEUTICALS, INC. (US) 2015-12-29 — — US disclosed
EP-2038291-A2 PROCESS FOR THE SYNTHESIS OF IBANDRONATE SODIUM Cipla Limited (IN) 2009-03-25 — — EP disclosed
WO-2008058722-A1 REAGENT AND USE THEREOF FOR THE PRODUCTION OF BISPHOSPHONATES SANDOZ A/S (DK) 2008-05-22 — — WO disclosed
EP-1923394-A1 Reagent and use thereof for the production of bisphosphonates Sandoz A/S (DK) 2008-05-21 — — EP disclosed
WO-2008035367-A2 PROCESS FOR THE SYNTHESIS OF IBANDRONATE SODIUM CIPLA LTD. (IN) 2008-03-27 — — WO disclosed
WO-2008035367-A2 PROCESS FOR THE SYNTHESIS OF IBANDRONATE SODIUM CIPLA LTD. (IN) 2008-03-27 — — WO disclosed
US-20070072859-A1 Pharmaceutical compounds ELI LILLY AND COMPANY (US) 2007-03-29 — — US disclosed
WO-2007013097-A1 IMPROVED PROCESS FOR THE PREPARATION OF IBANDRONATE SODIUM NATCO PHARMA LIMITED (IN) 2007-02-01 — — WO disclosed
US-5308735-A Aromatic-aldehyde resins, improved solubility NIPPON PAINT CO., LTD. (JP) 1994-05-03 — — US disclosed
EP-0540016-A1 Photosensitive resin and resin composition for lithographic printing Nippon Paint Co., Ltd. (JP) 1993-05-05 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160136233-A1 NOVEL CYCLOSPORIN ANALOGUES FOR PREVENTING OR TREATING HEPATITIS C INFECTION HAVCR2, CHP1, MAVS SIGMAR1 2750/4885CARM1 4797/4885PRMT6 4487/4885
US-20180086713-A1 CGAS IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) STING1, IRF3, CGAS SIGMAR1 4426/4885CARM1 4197/4885PRMT6 3389/4885
US-20070072859-A1 Pharmaceutical compounds ADRB3, HTR3C, SLC6A2 SIGMAR1 35/4885CARM1 2512/4885PRMT6 3286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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