SCHEMBL17264103

SCHEMBL17264103

Nc1ccc(N2CCC(C3CCN(c4ccc(N)c(F)c4)CC3)CC2)cc1F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.43
MAPK1 P28482 4/20 0.43
ALDH1A1 P00352 4/20 0.43
LMNA P02545 4/20 0.43
HTT P42858 3/20 0.43
GAA P10253 3/20 0.43
TDP1 Q9NUW8 3/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
S100B P04271 2/20 0.43
MEN1 O00255 1/20 0.43
PKM P14618 1/20 0.43
ALOX15 P16050 1/20 0.43
KMT2A Q03164 1/20 0.43
LGMN Q99538 4/20 0.42
KDM4E B2RXH2 1/20 0.41
RECQL P46063 1/20 0.41
PTK2B Q14289 1/20 0.41
IP6K1 Q92551 1/20 0.39
IDO1 P14902 2/20 0.39
TDO2 P48775 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17265646 0.87 MAPT (0.52) MAPTMAPK1ALDH1A1LMNAHTT
SCHEMBL28958012 0.86 LGMN (0.41) MAPTMAPK1ALDH1A1LMNAHTT
SCHEMBL25196226 0.83 MAPT (0.39) MAPTMAPK1ALDH1A1LMNAHTT
SCHEMBL22289269 0.83 ALDH1A1 (0.61) MAPTMAPK1ALDH1A1LMNAHTT
SCHEMBL3376365 0.83 ALDH1A1 (0.56) MAPTMAPK1ALDH1A1LMNAHTT
SCHEMBL20374556 0.82 NPY5R (0.41) MAPTMAPK1ALDH1A1LMNAHTT
SCHEMBL1127082 0.81 ALDH1A1 (0.65) MAPTMAPK1ALDH1A1LMNAHTT
SCHEMBL12005544 0.81 C1S (0.47) MAPTMAPK1ALDH1A1LMNATDP1
SCHEMBL22289404 0.80 NOTUM (0.40) MAPTMAPK1ALDH1A1LMNAHTT
SCHEMBL22289401 0.80 NOTUM (0.40) MAPTMAPK1ALDH1A1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9453164-B2 Liquid crystal alignment agent and uses thereof CHI MEI CORPORATION (TW) 2016-09-27 US disclosed
US-9453164-B2 Liquid crystal alignment agent and uses thereof CHI MEI CORPORATION (TW) 2016-09-27 US disclosed
US-20150329779-A1 LIQUID CRYSTAL ALIGNMENT AGENT AND USES THEREOF CHI MEI CORPORATION (TW) 2015-11-19 US disclosed
US-20150329779-A1 LIQUID CRYSTAL ALIGNMENT AGENT AND USES THEREOF CHI MEI CORPORATION (TW) 2015-11-19 US disclosed