SCHEMBL1127082

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22289269	0.98	ALDH1A1 (0.61)	ALDH1A1HTTMAPTGAAMAPK1
	SCHEMBL3376365	0.94	ALDH1A1 (0.56)	ALDH1A1HTTMAPTGAAMAPK1
	SCHEMBL17265646	0.90	MAPT (0.52)	ALDH1A1HTTMAPTGAAMAPK1
	SCHEMBL24196423	0.85	S100B (0.65)	ALDH1A1HTTMAPTGAAMAPK1
	SCHEMBL4461943	0.83	MAPT (0.59)	ALDH1A1HTTMAPTGAAMAPK1
	SCHEMBL6874430	0.82	S100B (0.61)	ALDH1A1HTTMAPTGAAMAPK1
	SCHEMBL2759980	0.82	MAPT (0.71)	ALDH1A1HTTMAPTGAAMAPK1
	SCHEMBL28168702	0.82	LMNA (0.54)	ALDH1A1HTTMAPTGAAMAPK1
	SCHEMBL8074303	0.82	MAPT (0.71)	ALDH1A1HTTMAPTGAAMAPK1
	SCHEMBL520439	0.81	LGMN (0.67)	ALDH1A1HTTMAPTGAAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.