Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7002194 | 0.80 | MAOA (0.53) | ALOX5KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL12553313 | 0.73 | ALOX5 (0.48) | ALOX5KMT2AMAOANUAK1IGF1R | |
| SCHEMBL27988072 | 0.70 | MAOA (0.57) | ALOX5HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL27987728 | 0.69 | ALOX5 (0.50) | ALOX5KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL2080972 | 0.69 | ALOX5 (0.50) | ALOX5KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL10788448 | 0.69 | BACE1 (0.50) | ALOX5HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL11257546 | 0.68 | BACE1 (0.41) | ALOX5KMT2ABACE1ADORA3ADORA2A | |
| SCHEMBL217083 | 0.68 | BACE1 (0.54) | ALOX5HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL29793269 | 0.67 | MAOB (0.47) | ALDH1A1HPGDHSD17B10ALOX15MAOA | |
| SCHEMBL78594 | 0.67 | MAOB (0.47) | ALDH1A1HPGDHSD17B10ALOX15MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150328245-A1 | Agents for Eliminating Tumour-Initiating Cells | GODAVARI BIOREFINERIES LIMITED (IN) | 2015-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150328245-A1 | Agents for Eliminating Tumour-Initiating Cells | MCL1, CD47, CD44 | ALOX5 272/4885HDAC4 932/4885HDAC2 2368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.