Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 9/20 | 0.53 |
| ▸ | MAOB | P27338 | 5/20 | 0.53 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | NEK2 | P51955 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.46 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.46 |
| ▸ | NEK6 | Q9HC98 | 1/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12553463 | 0.84 | MAOA (0.47) | MAOAMAOBAURKBKDRNUAK1 | |
| SCHEMBL6998523 | 0.80 | KDM4E (0.51) | MAOAMAOBAURKBKDRNUAK1 | |
| SCHEMBL17264241 | 0.80 | ALOX5 (0.44) | MAOAMAOBAURKBKDRNUAK1 | |
| SCHEMBL7001855 | 0.72 | MAPT (0.53) | MAOAMAOBAURKBKDRMEN1 | |
| SCHEMBL29793269 | 0.72 | MAOB (0.47) | MAOAMAOBAURKBKDRNUAK1 | |
| SCHEMBL78594 | 0.72 | MAOB (0.47) | MAOAMAOBAURKBKDRNUAK1 | |
| 5,7-Dihydroxy-4-Methylphthalide SCHEMBL3505368 | 0.72 | NUAK1 (0.58) | MAOAMAOBAURKBKDRNUAK1 | |
| SCHEMBL15680616 | 0.71 | KDM4E (0.46) | MAOAMAOBAURKBKDRNUAK1 | |
| SCHEMBL30487613 | 0.70 | MAOA (1.00) | MAOAMAOBAURKBKDRNUAK1 | |
| SCHEMBL20652853 | 0.69 | MAOA (0.50) | MAOAMAOBAURKBKDRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11731980-B1 | Furo[3,4-b]quinolone compounds as antibacterial agents | King Faisal University (SA) | 2023-08-22 | — | — | US | disclosed |
| US-11731980-B1 | Furo[3,4-b]quinolone compounds as antibacterial agents | King Faisal University (SA) | 2023-08-22 | — | — | US | disclosed |
| US-11731980-B1 | Furo[3,4-b]quinolone compounds as antibacterial agents | King Faisal University (SA) | 2023-08-22 | — | — | US | disclosed |
| EP-1241169-B1 | Isoindoloindolone derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-08-27 | — | — | EP | disclosed |
| US-6465660-B1 | PARTICULARLY 2-HYDROXY-8,9-DIMETHOXYISOINDOLO(2,1-A)INDOL-6-ONE AND 2-HYDROXY-8,9-DIMETHOXYISOINDOLO(2,1-A)INDOL-6-ONE; TREATING A DISORDER OF THE MELATONINERGIC SYSTEM | LES LABORATOIRES SERVIER (FR) | 2002-10-15 | — | — | US | disclosed |
| EP-1241169-A1 | Isoindoloindolone derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2002-09-18 | — | — | EP | disclosed |
| US-5849750-A | Dynemicin analogs | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1998-12-15 | — | — | US | disclosed |
| US-5763451-A | Dynemicin analogs | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1998-06-09 | — | — | US | disclosed |
| WO-1996003124-A9 | DYNEMICIN ANALOGS | — | 1996-03-14 | — | — | WO | disclosed |
| WO-1996003124-A1 | DYNEMICIN ANALOGS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1996-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11731980-B1 | Furo[3,4-b]quinolone compounds as antibacterial agents | TOP2A, TOP2B, TOP1 | MAOA 770/4885MAOB 381/4885AURKB 363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.