Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PROKR1 | Q8TCW9 | 6/20 | 0.36 |
| ▸ | FPR2 | P25090 | 5/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1725188 | 0.92 | MAPT (0.49) | MAPTPROKR1FPR2MAP3K14KMT2A | |
| SCHEMBL1724836 | 0.89 | MAPT (0.44) | MAPTPROKR1FPR2MAP3K14KMT2A | |
| SCHEMBL1727252 | 0.84 | MAPT (0.47) | MAPTMAP3K14KMT2AMAPK14PKM | |
| SCHEMBL29039033 | 0.80 | MAPT (0.51) | MAPTKMT2AMAPK14MEN1POLB | |
| SCHEMBL29097494 | 0.79 | MAPT (0.50) | MAPTPROKR1MAP3K14KMT2AMAPK14 | |
| SCHEMBL16402315 | 0.79 | MAPT (0.46) | MAPTPROKR1FPR2KMT2AALDH1A1 | |
| SCHEMBL173553 | 0.75 | PDE2A (0.47) | MAPTPROKR1FPR2MAPK14PKM | |
| SCHEMBL1726326 | 0.73 | MAPT (0.59) | MAPTKMT2AMAPK14PKMALDH1A1 | |
| SCHEMBL173619 | 0.73 | HSD11B1 (0.47) | MAPTKMT2AMAPK14HSD11B1 | |
| SCHEMBL29520229 | 0.73 | HSD11B1 (0.47) | MAPTKMT2AMAPK14HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403834-A1 | Fungicidal pyrazoles | E. I. du Pont de Nemours and Company (US) | 2012-01-11 | — | — | EP | claimed |