SCHEMBL17265385

SCHEMBL17265385

c1cncc(-c2ccc3c(c2)Oc2cccc4c2c-3cc2c3ccccc3c(-c3ccc(-c5cccc6ccccc56)cc3)cc42)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 5/20 0.44
KDM4E B2RXH2 4/20 0.43
ALDH1A1 P00352 2/20 0.43
MAPT P10636 2/20 0.43
HPGD P15428 2/20 0.43
RAB9A P51151 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CYP11B2 P19099 4/20 0.40
CYP19A1 P11511 2/20 0.40
CYP17A1 P05093 1/20 0.40
TNF P01375 1/20 0.40
PIK3CA P42336 1/20 0.37
PGR P06401 1/20 0.36
BACE1 P56817 1/20 0.36
KCNH2 Q12809 1/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
PDK2 Q15119 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19600401 0.91 KDM4E (0.46) CYP11B1KDM4EALDH1A1MAPTHPGD
SCHEMBL17265386 0.83 CA12 (0.38) KDM4EALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL17886385 0.82 KDM4E (0.39) CYP11B1KDM4EALDH1A1MAPTHPGD
SCHEMBL17265398 0.81 BRD4 (0.36) CYP11B1KDM4EALDH1A1MAPTHPGD
SCHEMBL19600426 0.81 CYP11B1 (0.41) CYP11B1KDM4EALDH1A1MAPTHPGD
SCHEMBL17265411 0.81 MAPK1 (0.36) KDM4EALDH1A1HPGDCA12CA1
SCHEMBL17265382 0.81 KDM4E (0.36) KDM4EALDH1A1MAPTHPGDRAB9A
SCHEMBL17265402 0.80 CA12 (0.36) KDM4EALDH1A1HPGDCA12CA1
SCHEMBL17265384 0.79 MAPK1 (0.40) KDM4EALDH1A1MAPTHPGDRAB9A
SCHEMBL17120180 0.79 CYP11B1 (0.39) CYP11B1KDM4ECYP11B2CYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9711736-B2 Condensed cyclic compound and organic light-emitting device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-18 US disclosed
US-9711736-B2 Condensed cyclic compound and organic light-emitting device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-18 US disclosed
US-20150333268-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-19 US disclosed
US-20150333268-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-19 US disclosed