SCHEMBL17265382

SCHEMBL17265382

c1ccc(-c2ccc3c(c2)Oc2cccc4c2c-3cc2c3ccccc3c(-c3ccccc3)cc42)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.36
MAPK1 P28482 2/20 0.36
ATM Q13315 2/20 0.36
HTT P42858 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
HPGD P15428 2/20 0.33
GPR84 Q9NQS5 2/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
POLB P06746 1/20 0.33
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
MAPT P10636 2/20 0.32
APAF1 O14727 1/20 0.32
NPC1 O15118 1/20 0.32
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.32
XBP1 P17861 1/20 0.32
PTBP1 P26599 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17265392 0.90 KDM4E (0.37) KDM4EMAPK1ATMSMN1; SMN2HPGD
SCHEMBL16805200 0.90 MEN1 (0.32) KDM4EMAPK1ATMMEN1KMT2A
SCHEMBL17265389 0.89 ALDH1A1 (0.42) KDM4EMAPK1ATMHPGDGPR84
SCHEMBL17265407 0.89 PLA2G2A (0.38) KDM4EMAPK1ATMSMN1; SMN2HPGD
SCHEMBL17265383 0.87 ALOX5 (0.38) KDM4EMAPK1ATMHPGDGPR84
SCHEMBL19600397 0.87 ATM (0.42) KDM4EMAPK1ATMHTTSMN1; SMN2
SCHEMBL17265386 0.87 CA12 (0.38) KDM4EMAPK1ATMSMN1; SMN2HPGD
SCHEMBL16805203 0.86 KDM4E (0.30) KDM4EMAPK1ATM
SCHEMBL17265421 0.86 KMT2A (0.37) KDM4EMAPK1ATMSMN1; SMN2HPGD
SCHEMBL17265400 0.86 KDM4E (0.36) KDM4EMAPK1ATMSMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9711736-B2 Condensed cyclic compound and organic light-emitting device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-18 US disclosed
US-9711736-B2 Condensed cyclic compound and organic light-emitting device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-18 US disclosed
US-20150333268-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-19 US disclosed
US-20150333268-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-19 US disclosed