SCHEMBL17265398

SCHEMBL17265398

c1ccc(-c2ccc3c(c2)Oc2cccc4c2c-3cc2c3ccccc3c(-c3ccc(-c5cccc6cccnc56)cc3)cc42)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.36
KDM4E B2RXH2 2/20 0.35
MAPK1 P28482 1/20 0.35
ATM Q13315 1/20 0.35
TOP1 P11387 6/20 0.34
ATR Q13535 1/20 0.33
MMP9 P14780 1/20 0.33
P2RX7 Q99572 1/20 0.32
METAP2 P50579 1/20 0.32
ENPP1 P22413 1/20 0.32
CYP11B1 P15538 1/20 0.32
PDE4A P27815 2/20 0.31
CKS1B P61024 1/20 0.31
GLO1 Q04760 1/20 0.31
SKP2 Q13309 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17265393 0.88 HSD17B10 (0.37) BRD4KDM4EMAPK1ATMMMP9
SCHEMBL17120192 0.86 KDM4E (0.33) BRD4KDM4EMAPK1ATMATR
SCHEMBL17265382 0.85 KDM4E (0.36) KDM4EMAPK1ATMALDH1A1MAPT
SCHEMBL17120177 0.83 KDM4E (0.34) BRD4KDM4EMAPK1ATMATR
SCHEMBL19600434 0.82 KDM4E (0.36) BRD4KDM4EMAPK1ATMMMP9
SCHEMBL17120223 0.81 FABP1 (0.39) KDM4EMAPK1ATMPDE4AGLO1
SCHEMBL17265385 0.81 CYP11B1 (0.44) KDM4EMAPK1ATMCYP11B1ALDH1A1
SCHEMBL17265392 0.81 KDM4E (0.37) KDM4EMAPK1ATMCYP11B1ALDH1A1
SCHEMBL17265389 0.81 ALDH1A1 (0.42) KDM4EMAPK1ATMCYP11B1ALDH1A1
SCHEMBL19600413 0.81 KDM4E (0.39) BRD4KDM4EMAPK1ATMMMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9711736-B2 Condensed cyclic compound and organic light-emitting device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-18 US disclosed
US-9711736-B2 Condensed cyclic compound and organic light-emitting device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-18 US disclosed
US-20150333268-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-19 US disclosed
US-20150333268-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-19 US disclosed