SCHEMBL17265393

SCHEMBL17265393

c1cnc2c(-c3cc4c5cccc6c5c(cc4c4ccccc34)-c3ccc(-c4cc5ccccc5c5ccccc45)cc3O6)cccc2c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.37
L3MBTL1 Q9Y468 3/20 0.37
MAPK1 P28482 2/20 0.37
ALDH1A1 P00352 2/20 0.37
HPGD P15428 2/20 0.37
TSHR P16473 2/20 0.37
HIF1A Q16665 2/20 0.37
CASP1 P29466 1/20 0.37
CYP11B1 P15538 1/20 0.36
KDM4E B2RXH2 3/20 0.35
ATM Q13315 1/20 0.35
BRD4 O60885 1/20 0.34
AVPR2 P30518 1/20 0.34
AVPR1A P37288 1/20 0.34
METAP2 P50579 1/20 0.32
GAA P10253 2/20 0.32
LMNA P02545 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
MAPT P10636 2/20 0.31
CDK2 P24941 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19600413 0.92 KDM4E (0.39) HSD17B10L3MBTL1MAPK1ALDH1A1HPGD
SCHEMBL19600434 0.89 KDM4E (0.36) HSD17B10L3MBTL1MAPK1ALDH1A1HPGD
SCHEMBL17265398 0.88 BRD4 (0.36) HSD17B10MAPK1ALDH1A1HPGDCYP11B1
SCHEMBL17265389 0.83 ALDH1A1 (0.42) HSD17B10L3MBTL1MAPK1ALDH1A1HPGD
SCHEMBL17886393 0.82 BRD4 (0.37) HSD17B10L3MBTL1MAPK1ALDH1A1HPGD
SCHEMBL17265419 0.81 ERN1 (0.36) HSD17B10MAPK1ALDH1A1HPGDKDM4E
SCHEMBL17120177 0.81 KDM4E (0.34) HSD17B10MAPK1ALDH1A1HPGDHIF1A
SCHEMBL17265395 0.81 ALOX5 (0.43) HSD17B10L3MBTL1MAPK1ALDH1A1HPGD
SCHEMBL17265417 0.81 CYP1A2 (0.43) HSD17B10L3MBTL1MAPK1ALDH1A1HPGD
SCHEMBL17120216 0.79 FABP1 (0.39) MAPK1KDM4EATMAVPR2AVPR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9711736-B2 Condensed cyclic compound and organic light-emitting device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-18 US disclosed
US-9711736-B2 Condensed cyclic compound and organic light-emitting device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-18 US disclosed
US-20150333268-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-19 US disclosed
US-20150333268-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-19 US disclosed