Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL918312 | 0.87 | APP (0.50) | APPEPHX2PTGS1PDE4ALMNA | |
| SCHEMBL901982 | 0.84 | — | — | |
| SCHEMBL2121438 | 0.84 | APP (0.48) | APPEPHX2PTGS1PDE4ALMNA | |
| SCHEMBL917868 | 0.83 | APP (0.42) | APPEPHX2PTGS1PDE4ALMNA | |
| SCHEMBL918374 | 0.83 | APP (0.42) | APPEPHX2PTGS1PDE4ALMNA | |
| SCHEMBL918086 | 0.83 | APP (0.42) | APPEPHX2PTGS1PDE4ALMNA | |
| SCHEMBL12541657 | 0.82 | APP (0.46) | APPEPHX2PTGS1PDE4ALMNA | |
| SCHEMBL7108955 | 0.81 | APP (0.50) | APPEPHX2PTGS1PDE4ALMNA | |
| SCHEMBL918521 | 0.81 | APP (0.41) | APPEPHX2PTGS1PDE4ALMNA | |
| SCHEMBL917692 | 0.81 | APP (0.41) | APPEPHX2PTGS1PDE4ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170275248-A1 | Carbondisulfide Derived Zwitterions | TPAT IP LLC | 2017-09-28 | — | — | US | disclosed |
| US-9676709-B2 | Carbondisulfide derived zwitterions | TPAT IP LLC | 2017-06-13 | — | — | US | disclosed |
| US-20170129853-A1 | Carbondisulfide Derived Zwitterions | TPAT IP LLC | 2017-05-11 | — | — | US | disclosed |
| US-9580385-B2 | Carbondisulfide derived zwitterions | TPAT IP LLC | 2017-02-28 | — | — | US | disclosed |
| US-20150329486-A1 | Carbondisulfide Derived Zwitterions | TPAT IP LLC | 2015-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170129853-A1 | Carbondisulfide Derived Zwitterions | SRM, PKD1, SLC7A11 | APP 4301/4885EPHX2 3568/4885PTGS1 3175/4885 |
| US-20170275248-A1 | Carbondisulfide Derived Zwitterions | SRM, PKD1, SLC7A11 | APP 4301/4885EPHX2 3568/4885PTGS1 3175/4885 |
| US-20150329486-A1 | Carbondisulfide Derived Zwitterions | SRM, PKD1, SLC7A11 | APP 4301/4885EPHX2 3568/4885PTGS1 3175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.