SCHEMBL17267258

SCHEMBL17267258

COc1cc(-c2cc(OC)cc(C(C)(C)C)c2OC(=O)OC(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.51

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
VCAM1 P19320 13/20 0.41
ELANE P08246 1/20 0.36
EGFR P00533 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19954350 0.91 CA1 (0.44) CA1CA2VCAM1ELANEEGFR
SCHEMBL17270588 0.86 CA1 (0.57) CA1CA2VCAM1EGFR
SCHEMBL17267257 0.86 CA1 (0.41) CA1CA2VCAM1ELANE
SCHEMBL17171700 0.86 CA1 (0.50) CA1CA2VCAM1ELANE
SCHEMBL17278384 0.84 SMN1; SMN2 (0.46) CA2VCAM1
SCHEMBL18202075 0.84 CA1 (0.54) CA1CA2VCAM1ELANEEGFR
SCHEMBL18950758 0.84 CA1 (0.38) CA1CA2VCAM1ELANE
SCHEMBL18950756 0.83 CA1 (0.37) CA1CA2VCAM1ELANE
SCHEMBL17274608 0.81 CA2 (0.67) CA1CA2VCAM1EGFR
SCHEMBL18682922 0.81 CA1 (0.43) CA1CA2VCAM1EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3145938-B1 METHOD FOR PRODUCING MONOPHOSPITES EVONIK DEGUSSA GMBH (DE) 2018-12-26 EP disclosed
EP-3145940-B1 METHOD FOR REDUCING THE CHLORINE CONTENT OF ORGANOMONOPHOSPHITES USING TWO SOLUTIONS EVONIK DEGUSSA GMBH (DE) 2018-12-12 EP disclosed
EP-3088405-B1 NOVEL MONOPHOSPHIT COMPOUNDS WITH A METHYL GROUP EVONIK DEGUSSA GMBH (DE) 2018-11-14 EP disclosed
US-9914681-B2 Preparation of high-quality oxo process alcohols from inconstant raw material sources EVONIK DEGUSSA GMBH (DE) 2018-03-13 US disclosed
EP-2947064-B1 PRODUCTION OF HIGH QUALITY OXO ALCOHOLS FROM VOLATILE RAW MATERIAL SOURCES EVONIK DEGUSSA GMBH (DE) 2018-01-17 EP disclosed
EP-2947064-B1 PRODUCTION OF HIGH QUALITY OXO ALCOHOLS FROM VOLATILE RAW MATERIAL SOURCES EVONIK DEGUSSA GMBH (DE) 2018-01-17 EP disclosed
US-9840524-B2 Process for reducing the chlorine content of organomonophosphites using two solutions EVONIK DEGUSSA GMBH (DE) 2017-12-12 US disclosed
US-9751904-B2 Method for reducing the chlorine content of organomonophosphites using dimethylaminobutane, triethylamine or triethanolamine EVONIK DEGUSSA GMBH (DE) 2017-09-05 US disclosed
EP-3178828-A1 HETEROCYCLIC SELENA PHOSPHITES AND METHOD FOR THE PRODUCTION THEREOF Evonik Degussa GmbH (DE) 2017-06-14 EP disclosed
EP-3178828-A1 HETEROCYCLIC SELENA PHOSPHITES AND METHOD FOR THE PRODUCTION THEREOF Evonik Degussa GmbH (DE) 2017-06-14 EP disclosed
US-20150336987-A1 NOVEL MONOPHOSPHITE LIGANDS HAVING A CARBONATE GROUP EVONIK INDUSTRIES AG (DE) 2015-11-26 US disclosed
WO-2015176929-A1 METHOD FOR REDUCING THE CHLORINE CONTENT OF ORGANOMONOPHOSPHITES USING DIMETHYLAMINOBUTANE, TRIETHYLAMINE OR TRIETHANOLAMINE EVONIK DEGUSSA GMBH (DE) 2015-11-26 WO disclosed
EP-2947089-A1 NOVEL MONOPHOSPHITE LIGANDS WITH A CARBONATE GROUP Evonik Degussa GmbH (DE) 2015-11-25 EP disclosed
EP-2947064-A1 PRODUCTION OF HIGH QUALITY OXO ALCOHOLS FROM VOLATILE RAW MATERIAL SOURCES Evonik Degussa GmbH (DE) 2015-11-25 EP disclosed
EP-2947091-A1 MIXTURES OF MONOPHOSPHITE LIGAND AND THEIR USE IN THE CATALYSIS OF A HYDROFORMYLATION REACTION Evonik Industries AG (DE) 2015-11-25 EP disclosed
EP-2947089-A1 NOVEL MONOPHOSPHITE LIGANDS WITH A CARBONATE GROUP Evonik Degussa GmbH (DE) 2015-11-25 EP disclosed
EP-2947090-A1 NOVEL MONOPHOSPHITE LIGANDS WITH A TERTIARY BUTYLOXYCARBONYL GROUP Evonik Industries AG (DE) 2015-11-25 EP disclosed
EP-2947091-A1 MIXTURES OF MONOPHOSPHITE LIGAND AND THEIR USE IN THE CATALYSIS OF A HYDROFORMYLATION REACTION Evonik Industries AG (DE) 2015-11-25 EP disclosed
EP-2947064-A1 PRODUCTION OF HIGH QUALITY OXO ALCOHOLS FROM VOLATILE RAW MATERIAL SOURCES Evonik Degussa GmbH (DE) 2015-11-25 EP disclosed
EP-2947090-A1 NOVEL MONOPHOSPHITE LIGANDS WITH A TERTIARY BUTYLOXYCARBONYL GROUP Evonik Industries AG (DE) 2015-11-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150336987-A1 NOVEL MONOPHOSPHITE LIGANDS HAVING A CARBONATE GROUP M6PR, NUDT1, PHOSPHO1 CA1 172/4885CA2 140/4885VCAM1 527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.