Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL172341 | 0.89 | SHBG (0.34) | SHBGEPHX1ALDH1A1TP53 | |
| SCHEMBL4744820 | 0.83 | SHBG (0.48) | SHBGEPHX1CA12CA1CA2 | |
| SCHEMBL6557485 | 0.81 | CA12 (0.47) | SHBGEPHX1CA12CA1CA2 | |
| SCHEMBL13995957 | 0.81 | MMP2 (0.38) | SHBGEPHX1CA12CA1CA2 | |
| SCHEMBL13995956 | 0.81 | MMP2 (0.38) | SHBGEPHX1CA12CA1CA2 | |
| SCHEMBL14011250 | 0.79 | CA12 (0.45) | SHBGEPHX1CA12CA1CA2 | |
| SCHEMBL25589732 | 0.79 | CA12 (0.45) | SHBGEPHX1CA12CA1CA2 | |
| SCHEMBL14011252 | 0.76 | CA12 (0.42) | SHBGEPHX1CA12CA1CA2 | |
| SCHEMBL27360797 | 0.75 | EPHX1 (0.47) | SHBGEPHX1CYP2C19GAACYP2C9 | |
| SCHEMBL13995808 | 0.74 | HTT (0.32) | EPHX1CA12CA1CA2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |