Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
| ▸ | ALPI | P09923 | 1/20 | 0.30 |
| ▸ | ALPG | P10696 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14541760 | 0.79 | SHBG (0.45) | EPHX1SHBGCYP2C19CYP2C9GAA | |
| SCHEMBL4744820 | 0.75 | SHBG (0.48) | EPHX1SHBGCYP2C19CYP2C9GAA | |
| SCHEMBL172674 | 0.75 | SHBG (0.48) | EPHX1SHBGCYP2C19CYP2C9GAA | |
| SCHEMBL1094949 | 0.74 | SHBG (0.52) | EPHX1SHBGALDH1A1SIGMAR1CYP1A2 | |
| SCHEMBL7761672 | 0.74 | SHBG (0.52) | EPHX1SHBGALDH1A1SIGMAR1CYP1A2 | |
| SCHEMBL5400953 | 0.73 | SHBG (0.62) | EPHX1SHBGALDH1A1CYP1A2 | |
| SCHEMBL7089601 | 0.73 | SHBG (0.46) | EPHX1SHBGALDH1A1SIGMAR1 | |
| SCHEMBL9209307 | 0.72 | SHBG (0.48) | EPHX1SHBGALDH1A1CYP1A2 | |
| SCHEMBL20600160 | 0.71 | SHBG (0.48) | EPHX1SHBGALDH1A1 | |
| SCHEMBL13540985 | 0.71 | SHBG (0.43) | EPHX1SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024036100-A1 | SUBSTITUTED TETRAZOLYL COMPOUNDS USEFUL AS T CELL ACTIVATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-02-15 | — | — | WO | disclosed |