Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.55 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | AHR | P35869 | 1/20 | 0.55 |
| ▸ | TXN | P10599 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20511196 | 0.95 | TXN (0.63) | NFKB1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL11837292 | 0.84 | NFKB1 (0.78) | NFKB1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL10851727 | 0.83 | POLA1 (0.59) | NFKB1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL9296086 | 0.80 | NR1I2 (0.55) | NFKB1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL9391146 | 0.80 | POLA1 (0.59) | NFKB1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL25463662 | 0.79 | NPC1 (0.45) | NFKB1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL18269844 | 0.79 | AGPAT2 (0.57) | NFKB1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL28177640 | 0.79 | CHRNA7 (0.55) | NFKB1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL6536659 | 0.79 | NPC1 (0.72) | NFKB1KDM4ENPC1RAB9AMAPT | |
| Dyrene SCHEMBL9328304 | 0.78 | TSHR (0.75) | NFKB1KDM4ENPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150328342-A1 | NOVEL TRICARBOCYANINE-CYCLODEXTRIN(S) CONJUGATES AND USE THEREOF | CYANAGEN S.R.L. (IT) | 2015-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150328342-A1 | NOVEL TRICARBOCYANINE-CYCLODEXTRIN(S) CONJUGATES AND USE THEREOF | KRTCAP2, DSC1, TBCD | NFKB1 3850/4885KDM4E 4369/4885NPC1 588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.