Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXN | P10599 | 1/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.51 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | AHR | P35869 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17268197 | 0.95 | NFKB1 (0.63) | TXNNFKB1KDM4ENPC1RAB9A | |
| SCHEMBL11837292 | 0.80 | NFKB1 (0.78) | TXNNFKB1KDM4ENPC1RAB9A | |
| SCHEMBL11785940 | 0.79 | NFKB1 (0.78) | TXNNFKB1KDM4ENPC1RAB9A | |
| SCHEMBL10851727 | 0.79 | POLA1 (0.59) | TXNNFKB1KDM4EMAPTMEN1 | |
| SCHEMBL13769425 | 0.78 | UCHL1 (0.55) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL20511159 | 0.77 | TXN (1.00) | TXNNFKB1KDM4ENPC1RAB9A | |
| SCHEMBL22214935 | 0.77 | TXN (0.69) | TXNNFKB1KDM4ENPC1MAPT | |
| SCHEMBL9296086 | 0.76 | NR1I2 (0.55) | TXNNFKB1KDM4EMAPTMEN1 | |
| SCHEMBL22214936 | 0.76 | TXN (0.67) | TXNNFKB1KDM4ENPC1RAB9A | |
| SCHEMBL9391146 | 0.75 | POLA1 (0.59) | NFKB1KDM4ENPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020146779-A1 | mTORC1 INHIBITORS FOR ACTIVATING AUTOPHAGY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-07-16 | — | — | WO | disclosed |
| WO-2018175958-A1 | THIOREDOXIN MODULATORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-09-27 | — | — | WO | disclosed |