Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015464 | 0.84 | MEN1 (0.40) | ALDH1A1KDM4ECASP7 | |
| SCHEMBL435759 | 0.82 | TAAR1 (0.48) | TAAR1IDO1ALDH1A1AOC3MAOB | |
| SCHEMBL31182394 | 0.79 | TAAR1 (0.52) | TAAR1IDO1ALDH1A1AOC3MAOB | |
| SCHEMBL125583 | 0.78 | ALDH1A1 (0.49) | TAAR1IDO1ALDH1A1MAOBMAPK1 | |
| SCHEMBL27561888 | 0.78 | TAAR1 (0.50) | TAAR1IDO1ALDH1A1AOC3MAOB | |
| SCHEMBL15066239 | 0.77 | TAAR1 (0.47) | TAAR1IDO1ALDH1A1AOC3MAOB | |
| SCHEMBL16371621 | 0.76 | MAPT (0.35) | ALDH1A1LMNAKDM4ECASP7 | |
| SCHEMBL18543737 | 0.76 | CTBP2 (0.47) | TAAR1ALDH1A1MAOBRAB9ACASP3 | |
| SCHEMBL251843 | 0.76 | AKR1B1 (0.56) | TAAR1IDO1KDM4E | |
| SCHEMBL15257739 | 0.75 | TAAR1 (0.42) | TAAR1IDO1ALDH1A1AOC3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3337785-B1 | PROCESS FOR THE PREPARATION OF LACTAMS FROM GLYOXYLIC ACID | UNILEVER PLC (GB) | 2020-03-18 | — | — | EP | disclosed |
| WO-2018115421-A1 | COMPOUNDS USEFUL FOR TREATING A MANNHEIMIA HAEMOLYTICA OR HISTOPHILUS SOMNI INFECTION | INTERVET INTERNATIONAL B.V. (NL) | 2018-06-28 | — | — | WO | disclosed |
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |