SCHEMBL125583

SCHEMBL125583

CC(=O)Cc1ccccc1F

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.49
MAOB P27338 1/20 0.49
MAPK1 P28482 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
IDO1 P14902 2/20 0.47
LMNA P02545 3/20 0.46
RAB9A P51151 2/20 0.46
KDM4E B2RXH2 2/20 0.46
TAAR1 Q96RJ0 3/20 0.45
RIPK1 Q13546 1/20 0.45
CXCL8 P10145 2/20 0.44
CASP3 P42574 1/20 0.44
CASP7 P55210 1/20 0.44
NPC1 O15118 1/20 0.44
NOD2 Q9HC29 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2949926 0.85 MAPK1 (0.47) ALDH1A1MAOBMAPK1L3MBTL1LMNA
SCHEMBL2206253 0.84 ALDH1A1 (0.48) ALDH1A1MAOBMAPK1LMNARAB9A
SCHEMBL6805430 0.84 L3MBTL1 (0.57) ALDH1A1MAPK1L3MBTL1LMNA
SCHEMBL28138968 0.83 ALB (0.45) ALDH1A1MAPK1L3MBTL1LMNARAB9A
SCHEMBL11205828 0.83 RIPK1 (0.46) ALDH1A1MAOBL3MBTL1KDM4ERIPK1
SCHEMBL4661911 0.82 ALDH1A1 (0.51) ALDH1A1MAPK1IDO1LMNARAB9A
SCHEMBL6969660 0.82 ALDH1A1 (0.51) ALDH1A1MAPK1IDO1LMNARAB9A
SCHEMBL435759 0.82 TAAR1 (0.48) ALDH1A1MAOBMAPK1IDO1LMNA
SCHEMBL28357376 0.82 ANO1 (0.47) ALDH1A1MAOBMAPK1L3MBTL1KDM4E
SCHEMBL9102212 0.82 P2RX7 (0.45) ALDH1A1MAOBL3MBTL1RAB9ARIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115219637-B Method for analyzing flavor substances and mouthfeel and taste of salty fresh seasoning 广州城市职业学院 2023-10-20 CN claimed
CN-114950159-B Preparation method of aromatic polymer separation membrane based on super acid catalysis 南京工业大学 2023-06-06 CN claimed
CN-116082203-A Shulin acid intermediate impurity and preparation method thereof 宁波大红鹰药业股份有限公司 2023-05-09 CN claimed
CN-114094098-A Metal lithium powder composite material, preparation method, silica cathode and lithium ion battery 上海卡耐新能源有限公司 2022-02-25 CN claimed
CN-104710256-A Cheap and efficient synthesis method of alpha-hydroxyketone compound UNIV BEIJING 2015-06-17 CN claimed
CN-101891569-B Preparation method of alpha-aromatic ketone compound UNIV WUHAN 2013-07-24 CN claimed
EP-2499147-A2 IMPROVED PROCESSES FOR PREPARING PRASUGREL AND PHARMACEUTICALLY ACCEPTABLE SALTS THEROEOF MSN Laboratories Limited (IN) 2012-09-19 EP claimed
US-20120202066-A1 Processes For Preparing Prasugrel And Pharmaceutically Acceptable Salts Thereof MSN LABORATORIES LIMITED (IN) 2012-08-09 US claimed
WO-2011042918-A2 NOVEL AND IMPROVED PROCESSES FOR THE PREPARATION OF PRASUGREL, ITS INTERMEDIATES AND PHARMACEUTICALLY ACCEPTABLE SALTS MSN LABORATORIES LIMITED (IN) 2011-04-14 WO claimed
CN-101429193-A Process for producing 1-tetrahydropyran-3-methyl-5-amido indazole UNIV NANCHANG HANGKONG (CN) 2009-05-13 CN claimed
EP-4665738-A1 MIXED P,N-DONOR LIGANDS, THEIR COMPLEXES AND USE THEREOF Umicore AG & Co. KG (DE) 2025-12-24 EP disclosed
US-20250381187-A1 KRAS G12C INHIBITORS AND METHODS OF USING THE SAME AMGEN INC. (US) 2025-12-18 US disclosed
US-12440491-B2 KRAS G12C inhibitors and methods of using the same AMGEN INC. (US) 2025-10-14 US disclosed
US-20250049036-A1 SUBSTITUTED FUSED BICYCLIC PYRIDINE CARBOXAMIDE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI PI INDUSTRIES LTD. (IN) 2025-02-13 US disclosed
CN-119040289-A Amine dehydrogenase and encoding nucleic acid and application thereof 河北工业大学 2024-11-29 CN disclosed
WO-1994024098-A1 Ξ-FLUOROSULPHONIMIDES, METHOD OF PREPARING THEM AND THEIR USE AS FLUORINATION AGENTS SCHERING AKTIENGESELLSCHAFT (DE) 1994-10-27 WO disclosed
US-5288726-A Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation UBE INDUSTRIES LIMITED (JP) 1994-02-22 US disclosed
EP-0542411-A2 Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation Sankyo Company Limited (JP) 1993-05-19 EP disclosed
EP-0200942-A2 New derivatives of an aminoketone NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1986-11-12 EP disclosed
US-3998971-A Novel N-vinyloxyethyl-α-methyl-β-phenethylamines for depressing appetite ABBOTT LABORATORIES (US) 1976-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250049036-A1 SUBSTITUTED FUSED BICYCLIC PYRIDINE CARBOXAMIDE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CBR3, C5, CBR1 ALDH1A1 3438/4885MAOB 602/4885MAPK1 1510/4885
US-20250381187-A1 KRAS G12C INHIBITORS AND METHODS OF USING THE SAME KRAS, NRAS, HRAS ALDH1A1 4162/4885MAOB 4809/4885MAPK1 1073/4885
US-12440491-B2 KRAS G12C inhibitors and methods of using the same KRAS, NRAS, HRAS ALDH1A1 4162/4885MAOB 4809/4885MAPK1 1073/4885
US-20120202066-A1 Processes For Preparing Prasugrel And Pharmaceutically Acceptable Salts Thereof SF1, PFKP, CYP2F1 ALDH1A1 340/4885MAOB 2182/4885MAPK1 507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.