Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 15/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | GLA | P06280 | 3/20 | 0.68 |
| ▸ | GAA | P10253 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | SNCA | P37840 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | RORC | P51449 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2628263 | 1.00 | APP (1.00) | APPMAPTGLAGAAKDM4E | |
| Hydrochloric Acid SCHEMBL38731 | 0.98 | APP (0.97) | APPMAPTGLAGAAKDM4E | |
| Ammonia Solution, Strong SCHEMBL27534538 | 0.98 | APP (0.97) | APPMAPTGLAGAAKDM4E | |
| SCHEMBL13853558 | 0.97 | APP (0.94) | APPMAPTGLAGAAKDM4E | |
| SCHEMBL1982962 | 0.92 | APP (0.85) | APPMAPTGLAGAAKDM4E | |
| SCHEMBL1982961 | 0.92 | APP (0.85) | APPMAPTGLAGAAKDM4E | |
| SCHEMBL21771267 | 0.88 | APP (0.78) | APPMAPTGLAGAAKDM4E | |
| SCHEMBL12422217 | 0.87 | MAPT (0.81) | APPMAPTGLAGAAKDM4E | |
| SCHEMBL13341214 | 0.86 | APP (0.73) | APPMAPTGLAGAAKDM4E | |
| SCHEMBL2633341 | 0.85 | APP (0.73) | APPMAPTGLAGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3034654-B1 | Composition and method for micro etching of copper and copper alloys | ATOTECH DEUTSCHLAND GMBH (DE) | 2017-10-25 | — | — | EP | claimed |
| EP-2241653-B1 | Composition and method for micro etching of copper and copper alloys | ATOTECH DEUTSCHLAND GMBH (DE) | 2017-09-06 | — | — | EP | claimed |
| US-11666661-B2 | Methods and compounds for targeted autophagy | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-06 | — | — | US | disclosed |
| US-11666661-B2 | Methods and compounds for targeted autophagy | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-06 | — | — | US | disclosed |
| US-20220387411-A1 | TARGETED AUTOPHAGY CONJUGATES AND METHODS | VULCAN BIO CORPORATION | 2022-12-08 | — | — | US | disclosed |
| US-20190290778-A1 | METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY | FRONTIER MEDICINES CORPORATION | 2019-09-26 | — | — | US | disclosed |
| US-20180028694-A1 | THIOFLAVIN DERIVATIVES FOR USE IN ANTEMORTEM DIAGNOSIS OF ALZHEIMER'S DISEASE AND IN VIVO IMAGING AND PREVENTION OF AMYLOID DEPOSITION | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2018-02-01 | — | — | US | disclosed |
| US-9833458-B2 | Thioflavin derivatives for use in the antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2017-12-05 | — | — | US | disclosed |
| US-9808541-B2 | Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition | University of Pittsburgh—Of the Commonwealth System of Higher Eduation (US) | 2017-11-07 | — | — | US | disclosed |
| US-9808541-B2 | Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition | University of Pittsburgh—Of the Commonwealth System of Higher Eduation (US) | 2017-11-07 | — | — | US | disclosed |
| EP-2042501-B1 | COMPOUND HAVING AFFINITY FOR AMYLOID | NIHON MEDIPHYSICS CO LTD (JP) | 2017-04-12 | — | — | EP | disclosed |
| EP-2098522-A1 | NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2009-09-09 | — | — | EP | disclosed |
| US-20090085018-A1 | COLORED CURABLE COMPOSITION, COLOR FILTER, AND SOLID IMAGE PICKUP ELEMENT | FUJIFILM CORPORATION (JP) | 2009-04-02 | — | — | US | disclosed |
| US-20090085018-A1 | COLORED CURABLE COMPOSITION, COLOR FILTER, AND SOLID IMAGE PICKUP ELEMENT | FUJIFILM CORPORATION (JP) | 2009-04-02 | — | — | US | disclosed |
| EP-2042501-A1 | NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2009-04-01 | — | — | EP | disclosed |
| EP-2022792-A1 | NOVEL COMPOUND HAVING AFFINITY TO AMYLOID | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2009-02-11 | — | — | EP | disclosed |
| EP-2019103-A1 | NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2009-01-28 | — | — | EP | disclosed |
| US-20080154042-A1 | THIOFLAVIN DERIVATIVES FOR USE IN THE ANTEMORTEM DIAGNOSIS OF ALZHEIMERS DISEASE AND IN VIVO IMAGING AND PREVENTION OF AMYLOID DEPOSITION | UNIVERSITY OF PITTSBURGH | 2008-06-26 | — | — | US | disclosed |
| US-7351401-B2 | Thioflavin derivatives for use in the antemortem diagnosis of Alzheimers disease and in vivo imaging and prevention of amyloid deposition | UNIVERSITY OF PITTSBURGH (US) | 2008-04-01 | — | — | US | disclosed |
| US-7270800-B2 | Imaging amyloid deposits in living patients, with an amyloid binding agents having radiolabeled iodine; radiotherapy | UNIVERSITY OF PITTSBURGH (US) | 2007-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220387411-A1 | TARGETED AUTOPHAGY CONJUGATES AND METHODS | ATG7, BECN1, SQSTM1 | APP 3052/4885MAPT 198/4885GLA 1700/4885 |
| US-20080154042-A1 | THIOFLAVIN DERIVATIVES FOR USE IN THE ANTEMORTEM DIAGNOSIS OF ALZHEIMERS DISEASE AND IN VIVO IMAGING AND PREVENTION OF AMYLOID DEPOSITION | APP, PSEN2, MAPT | APP 1/4885MAPT 3/4885GLA 189/4885 |
| US-20190290778-A1 | METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY | ATG7, BECN1, SQSTM1 | APP 3003/4885MAPT 442/4885GLA 1341/4885 |
| US-20180028694-A1 | THIOFLAVIN DERIVATIVES FOR USE IN ANTEMORTEM DIAGNOSIS OF ALZHEIMER'S DISEASE AND IN VIVO IMAGING AND PREVENTION OF AMYLOID DEPOSITION | APP, PSEN2, MAPT | APP 1/4885MAPT 3/4885GLA 180/4885 |
| US-11666661-B2 | Methods and compounds for targeted autophagy | ATG7, BECN1, SQSTM1 | APP 3003/4885MAPT 442/4885GLA 1341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.