Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 11/20 | 0.55 |
| ▸ | JAK1 | P23458 | 11/20 | 0.55 |
| ▸ | TYK2 | P29597 | 11/20 | 0.55 |
| ▸ | JAK3 | P52333 | 11/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15019951 | 0.88 | L3MBTL1 (0.56) | HDAC6L3MBTL1NPC1ALDH1A1LMNA | |
| SCHEMBL20454715 | 0.85 | RORC (0.48) | JAK2JAK1TYK2JAK3HDAC6 | |
| SCHEMBL15020122 | 0.85 | KDM4E (0.49) | HDAC6NPC1ALDH1A1LMNATSHR | |
| SCHEMBL18432868 | 0.82 | BACE1 (0.47) | JAK2JAK1TYK2JAK3HTR6 | |
| SCHEMBL27476706 | 0.80 | L3MBTL1 (0.49) | L3MBTL1 | |
| SCHEMBL1726928 | 0.75 | JAK2 (0.60) | JAK2JAK1TYK2JAK3HDAC6 | |
| SCHEMBL1726103 | 0.73 | JAK2 (0.58) | JAK2JAK1TYK2JAK3HDAC6 | |
| SCHEMBL3727866 | 0.72 | KMT2A (0.67) | JAK2JAK1TYK2JAK3KMT2A | |
| SCHEMBL19437535 | 0.72 | KMT2A (0.55) | JAK2JAK1TYK2JAK3KMT2A | |
| SCHEMBL3399930 | 0.72 | HDAC6 (0.50) | HDAC6KMT2ANPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403852-A1 | 3H-IMIDAZO [4, 5 -C]PYRIDINE- 6 -CARBOXAMIDES AS ANTI- INFLAMMATORY AGENTS | Boehringer Ingelheim International GmbH (DE) | 2012-01-11 | — | — | EP | disclosed |